Blank Cover Image

Trajectories of Postload Plasma Glucose in the Development of Type 2 Diabetes in Japanese Adults

フォーマット:
論文
責任表示:
Oka, Rie ; Shibata, Kyoko ; Sakurai, Masaru ; Kometani, Mitsuhiro ; Yamagishi, Masakazu ; Yoshimura, Kenichi ; Yoneda, Takashi ; 大家, 理恵 ; 柴田, 恭子 ; 櫻井, 勝 ; 米谷, 充弘 ; 山岸, 正和 ; 吉村, 健一 ; 米田, 隆
言語:
英語
出版情報:
Hindawi Limited, 2017-09-14
著者名:
Oka, Rie
Shibata, Kyoko
Sakurai, Masaru
Kometani, Mitsuhiro
Yamagishi, Masakazu
Yoshimura, Kenichi
Yoneda, Takashi
大家, 理恵
柴田, 恭子
櫻井, 勝
米谷, 充弘
山岸, 正和
吉村, 健一
米田, 隆
続きを見る
掲載情報:
Journal of Diabetes Research
ISSN:
2314-6745  CiNii Research  Webcat Plus  JAIRO
巻:
2017
開始ページ:
5307523
バージョン:
publisher
概要:
金沢大学附属病院研修医・専門医総合教育センター<br />We aimed to clarify how the trajectories of 1-hour postload plasma glucose (PG) and 2-hour PG were different in the development of type 2 diabetes. Using data of repeated health checkups in Japanese worker s from April 2006 to March 2016, longitudinal changes of fasting, 1-hour, and 2-hour PG on the oral glucose tolerance test were analyzed with a linear mixed effects model. Of the 1464 nondiabetic subjects at baseline, 112 subjects progressed to type 2 diabetes during the observation period (progressors). In progressors, 1-hour PG and 2-hour PG showed gradual increases with slopes of 1.33 ± 0.2 and 0.58 ± 0.2 mg/dL/year, respectively, followed by a steep increase by which they attained diabetes. Until immediately before the diabetes transition, age- and sex-adjusted mean level of 2-hour PG was 149 ± 2.7 mg/dL, 34 ± 2.7 (30%) higher compared to nonprogressors, while that of 1-hour PG was 206 ± 4.1 mg/dL, 60 ± 4.3 mg/dL (41%) higher compared to nonprogressors. In conclusion, diabetes transition was preceded by a mild elevation of 2-hour PG for several years or more. The elevation in 1-hour PG was larger than that of 2-hour PG until immediately before the transition to diabetes. © 2017 Rie Oka et al.<br />Embargo Period 12 months 続きを見る
URL:
http://hdl.handle.net/2297/00049541
タイトル・著者・出版者が同じ資料

類似資料:

1
 
2
 
3
 
4
 
5
 
6
 
7
 
8
 
9
 
10
 
11
 
12
 

Wakabayashi, Yusuke, Oka, Rie, Nakaya, Masako, Karashima, Shigehiro, Kometani, Mitsuhiro, Sakurai, Masaru, Yoshimura, &hellip;

Hindawi Publishing Corporation

Oka, Rie, Kobayashi, Junji, Inazu, Akihiro, Yagi, Kunimasa, Miyamoto, Susumu, Sakurai, Masaru, Nakamura, Koshi, Miura, &hellip;

Elsevier

Oka, Rie, Nomura, Akihiro, Yasugi, Ayaka, Kometani, Mitsuhiro, Gondoh, Yuko, Yoshimura, Kenichi, Yoneda, Takashi, &hellip;

Springer (part of Springer Nature)

Sugihara, Masako, Oka, Rie, Sakurai, Masaru, Nakamura, Koshi, Moriuchi, Tadashi, Miyamoto, Susumu, Takeda, Yoshiyu, &hellip;

Japanese Society of Internal Medicine = 日本内科学会

Aono, Daisuke, Oka, Rie, Kometani, Mitsuhiro, Takeda, Yoshimichi, Karashima, Shigehiro, Yoshimura, Kenichi, Takeda, &hellip;

Hindawi Publishing Corporation

Oka, Rie, Yagi, Kunimasa, Sakurai, Masaru, Nakamura, Koshi, Nagasawa, Shin-ya, Miyamoto, Susumu, Nohara, Atsushi, &hellip;

Japan Atherosclerosis Society = 日本動脈硬化学会

蘇馬, 由衣, 大家, 理恵, 藤井, 寿美枝, 伊藤, 直子, 米谷, 充弘, 唐島, 成宙, 武田, 仁勇, &hellip;

日本老年医学会 = The Japan Geriatrics Society

Moriuchi, Tadashi, Oka, Rie, Yagi, Kunimasa, Miyamoto, Susumu, Nomura, Hideki, Yamagishi, Masakazu, Mabuchi, Hiroshi, &hellip;

Japanese Society of Internal Medicine = 日本内科学会

Karashima, Shigehiro, Yoneda, Takashi, Kometani, Mitsuhiro, Ohe, Masashi, Mori, Shunsuke, Sawamura, Toshitaka, Furukawa, &hellip;

日本高血圧学会 = Japanese Society of Hypertension

Kometani, Mitsuhiro, Yoneda, Takashi, Demura, Masashi, Karashima, Shigehiro, Mori, Shunsuke, Oe, Masashi, Sawamura, &hellip;

Japanese Society of Internal Medicine = 日本内科学会