Successful treatment with recombinant thrombomodulin for B-cell lymphoma-associated hemophagocytic syndrome complicated by disseminated intravascular coagulation

フォーマット:

論文

責任表示:

Uni, Masahiro ; Yoshimi, Akihide ; Maki, Hiroaki ; Maeda, Daichi ; Nakazaki, Kumi ; Nakamura, Fumihiko ; Fukayama, Masashi ; Kurokawa, Mineo ; 前田, 大地

言語:

英語

出版情報:

e-Century Publishing, 2013-05-15

著者名:

Uni, Masahiro

Yoshimi, Akihide

Maki, Hiroaki

Maeda, Daichi

Nakazaki, Kumi

Nakamura, Fumihiko

Fukayama, Masashi

Kurokawa, Mineo

前田, 大地

続きを見る

掲載情報:

International Journal of Clinical and Experimental Pathology

ISSN:

1936-2625      

巻:

6

通号:

6

開始ページ:

1190

終了ページ:

1194

バージョン:

publisher

概要:

金沢大学医薬保健研究域医学系<br />We report here a 47-year-old male with the diagnosis of high-grade B-cell lymphoma and hemophagocytosis accompanying disseminated intravascular coagulation (DIC). Lymphoma-associated hemophagocytic syndrome (LAHS) … is a life-threatening disorder, and LAHS secondary to B-cell lymphoma is relatively rare compared to that secondary to T- or NK/T-cell lymphoma in Western countries. T- or NK/T-cell LAHS is sometimes combined with DIC, which makes patients' outcomes even worse, but few reports of B-cell LAHS accompanying DIC has been published so far. We successfully treated a patient with this condition with recombinant thrombomodulin (rTM), a novel agent for DIC. We believe that rTM is a therapeutic option in cases with B-cell LAHS accompanying DIC. 続きを見る

URL:

http://hdl.handle.net/2297/00062691