Transformation of p53-positive papillary thyroid carcinoma to anaplastic carcinoma of the liver following postoperative radioactive iodine-131 therapy

Transformation of p53-positive papillary thyroid carcinoma to anaplastic carcinoma of the liver following postoperative radioactive iodine-131 therapy

フォーマット:

論文

責任表示:

Takeshita, Yumie ; Takamura, Toshinari ; Minato, Hiroshi ; Misu, Hirofumi ; Ando, Hitoshi ; Yamashita, Tatsuya ; Ikeda, Hiroko ; Nakanuma, Yasuni ; Kaneko, Shuichi

言語:

英語

出版情報:

日本内科学会 = the Japanese Society of Internal Medicine, 2008-01-01

著者名:

掲載情報:

Internal Medicine

ISSN:

0918-2918

巻:

47

通号:

19

開始ページ:

1709

終了ページ:

1712

バージョン:

publisher

概要:

金沢大学医薬保健研究域医学系<br />金沢大学医薬保健研究域医学系恒常性制御学<br />Multiple liver metastases were incidentally detected in the lobe of the liver of an 81-year-old woman following total thyroidectomy and ablative radioactive iodine administration for … the treatment of papillary thyroid carcinoma. A biopsy specimen taken from the metastatic liver tumor was histologically diagnosed as anaplastic carcinoma. Immunohistochemical staining for p53 was positive in both the primary tumor and liver biopsy specimens. We considered this to have been caused by anaplastic transformation from papillary thyroid carcinoma during treatment. We report a rare case of multiple liver metastases from a papillary thyroid carcinoma, which we believe to be the result of anaplastic transformation during postoperative radioactive iodine-131 therapy. © 2008 The Japanese Society of Internal Medicine. 続きを見る

URL:

http://hdl.handle.net/2297/14444

タイトル・著者・出版者が同じ資料

詳細

主題:	Anaplastic transformation; Differentiated thyroid carcinoma; Iodine-131 therapy; Liver; p53 mutations
受理日:	2008-01-01

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