Reactive peripheral blood plasmacytosis in a patient with acute hepatitis A

Reactive peripheral blood plasmacytosis in a patient with acute hepatitis A

フォーマット:

論文

責任表示:

Wada, Taizo ; Maeba, Hideaki ; Ikawa, Yasuhiro ; Hashida, Yoko ; Okumura, Akiko ; Shibata, Fumie ; Tone, Yumi ; Inoue, Masayuki ; Koizumi, Shoichi ; Takatori, Hajime ; Sakai, Yoshio ; Kaneko, Shuichi ; Yachie, Akihiro

言語:

英語

出版情報:

日本血液学会 = Japanese Society of Hematology, 2007-04-01

著者名:

掲載情報:

International Journal of Hematology

ISSN:

0925-5710

巻:

85

通号:

3

開始ページ:

191

終了ページ:

194

バージョン:

publisher

概要:

金沢大学附属病院小児科<br />Reactive plasmacytosis is a transient expansion of plasma cell progenitors and precursors. This rare condition has been reported to occur mainly in infections and tumors. We describe a case of acute hepatitis A presen … ting with marked peripheral blood plasmacytosis. Plasma cells made up 27.5% of the mononuclear cells and had the immunophenotype CD10-CD19 +CD20-CD21-CD23-CD34 -CD38++HLA-DR+. Although the level of interleukin 6 was not increased, the presence of activated T-cells with an inverted CD4/CD8 ratio and high levels of soluble interleukin 2 receptor and neopterin indicated a marked immune response to acute hepatitis A. The patient's plasma cells had almost disappeared from the blood by hospital day 16. This report may represent the first described case of reactive peripheral blood plasmacytosis in acute hepatitis A. © 2007 The Japanese Society of Hematology. 続きを見る

URL:

http://hdl.handle.net/2297/16857

タイトル・著者・出版者が同じ資料

詳細

主題:	Hepatitis A; Immune respons; Peripheral blood; Reactive plasmacytosis
受理日:	2007-04-01

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