Autoantibody to dihydropyridine receptor in myasthenia gravis

Autoantibody to dihydropyridine receptor in myasthenia gravis

フォーマット:

論文

責任表示:

Maruta, Takahiro ; Yoshikawa, Hiroaki ; Fukasawa, Shuichi ; Umeshita, Sho ; Inaoka, Yoshihiro ; Edahiro, Shigeki ; Kado, Hirotsugu ; Motozaki, Yuko ; Iwasa, Kazuo ; Yamada, Masahito

言語:

英語

出版情報:

Elsevier BV, 2009-03-31

著者名:

掲載情報:

Journal of Neuroimmunology

ISSN:

0165-5728

巻:

208

通号:

1-2

開始ページ:

125

終了ページ:

129

バージョン:

author

概要:

金沢大学保健管理センター<br />To investigate autoantibodies related to excitation-contraction (E-C) coupling in patients with myasthenia gravis (MG), we developed a novel method to detect autoantibodies against dihydropyridine receptor (DHPR). Us … ing this method, we detected DHPR antibody in 37% (11 out of 30) of MG patients with thymoma. Antibodies were not detected in normal nor disease controls. The titer of DHPR antibodies showed no significant correlation with autoantibodies to acetylcholine nor ryanodine receptors. The DHPR antibody is another marker for thymoma in MG, and it might have some role in clinical symptoms related to E-C coupling. © 2009 Elsevier B.V. All rights reserved. 続きを見る

URL:

http://hdl.handle.net/2297/17330

タイトル・著者・出版者が同じ資料

詳細

主題:	Autoantibody; Dihydropyridine receptor; Excitation-contraction coupling; Myasthenia gravis; Ryanodine receptor; Thymoma
受理日:	2009-03-31

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