※一部利用できない機能があります
Middle-aged Japanese women are resistant to obesity-related metabolic abnormalities
- フォーマット:
- 論文
- 責任表示:
- Sakurai, Masaru ; Takamura, Toshinari ; Miura, Katsuyuki ; Kaneko, Shuichi ; Nakagawa, Hideaki
- 言語:
- 英語
- 出版情報:
- Elsevier, 2009-04-01
- 著者名:
- 掲載情報:
- Metabolism: Clinical and Experimental
- ISSN:
- 0026-0495
- 巻:
- 58
- 通号:
- 4
- 開始ページ:
- 456
- 終了ページ:
- 459
- バージョン:
- author
- 概要:
- 金沢大学医薬保健研究域医学系<br />We attempted to determine sex differences in obesity-related metabolic abnormalities in a relatively large middle-aged Japanese population. The study population consisted of 2935 men and 1622 women who were 35 to 5 … 9 years old. Metabolic abnormalities were determined using the Japanese criteria for metabolic syndrome, and we evaluated the number of metabolic abnormalities discriminated by waist circumference. In men, the mean number of metabolic abnormalities increased as the waist circumference increased. In women, although the mean number of metabolic abnormalities increased as the waist circumference increased, the mean number was less than 1 even in those with a waist circumference of at least 95 cm. According to the receiver operating characteristic curve, the cutoff levels yielding the maximal sensitivity plus specificity for predicting the prevalence of one or more obesity-related metabolic abnormalities were 80 cm in men and 73 cm in women. However, the positive predictive value was as low as 28.8% in men and 7.1% in women, which may not be suitable for a screening test, especially in women. Middle-aged Japanese women seem to be resistant to obesity-induced metabolic abnormalities, and waist circumference would not effectively predict the existence of metabolic syndrome. In setting the cutoff points in guidelines, a greater emphasis should be placed on the absolute risk of having abnormalities or diseases. © 2009 Elsevier Inc. All rights reserved. 続きを見る
- URL:
- http://hdl.handle.net/2297/17359
類似資料:
Japanese Society of Internal Medicine = 日本内科学会 |
日本内科学会 = The Japanese Society of Internal Medicine |
Asian Association for the Study of Diabetes / Blackwell Publishing | |
Asian Association for the Study of Diabetes / Wiley-Blackwell | |
日本内科学会 = The Japanese Society of Internal Medicine |