Attenuation correction of myocardial SPECT by scatter-photopeak window method in normal subjects

フォーマット:

論文

責任表示:

Okuda, Koichi ; Nakajima, Kenichi ; Motomura, Nobutoku ; Kubota, Masahiro ; Yamaki, Noriyasu ; Maeda, Hisato ; Matsuo, Shinro ; Kinuya, Seigo

言語:

英語

出版情報:

2009-07-01

著者名:

Okuda, Koichi

Nakajima, Kenichi

Motomura, Nobutoku

Kubota, Masahiro

Yamaki, Noriyasu

Maeda, Hisato

Matsuo, Shinro

Kinuya, Seigo

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掲載情報:

Annals of Nuclear Medicine

ISSN:

0914-7187      

巻:

23

通号:

5

開始ページ:

501

終了ページ:

506

バージョン:

author

概要:

金沢大学医薬保健研究域<br />Objective: Segmentation with scatter and photopeak window data using attenuation correction (SSPAC) method can provide a patient-specific non-uniform attenuation coefficient map only by using photopeak and scatter ima … ges without X-ray computed tomography (CT). The purpose of this study is to evaluate the performance of attenuation correction (AC) by the SSPAC method on normal myocardial perfusion database. Methods: A total of 32 sets of exercise-rest myocardial images with Tc-99 m-sestamibi were acquired in both photopeak (140 keV ± 10%) and scatter (7% of lower side of the photopeak window) energy windows. Myocardial perfusion databases by the SSPAC method and non-AC (NC) were created from 15 female and 17 male subjects with low likelihood of cardiac disease using quantitative perfusion SPECT software. Segmental myocardial counts of a 17-segment model from these databases were compared on the basis of paired t test. Results: AC average myocardial perfusion count was significantly higher than that in NC in the septal and inferior regions (P < 0.02). On the contrary, AC average count was significantly lower in the anterolateral and apical regions (P < 0.01). Coefficient variation of the AC count in the mid, apical and apex regions was lower than that of NC. Conclusions: The SSPAC method can improve average myocardial perfusion uptake in the septal and inferior regions and provide uniform distribution of myocardial perfusion. The SSPAC method could be a practical method of attenuation correction without X-ray CT. © 2009 The Japanese Society of Nuclear Medicine. 続きを見る

URL:

http://hdl.handle.net/2297/18232