Immunoglobulin light-chain (AL) amyloidosis with myasthenic symptoms and echocardiographic features of dilated cardiomyopathy

フォーマット:

論文

責任表示:

Yoshita, Mitsuhiro ; Ishida, Chiho ; Yanase, Daisuke ; Yamada, Masahito

言語:

英語

出版情報:

The Japanese Society of Internal Medicine = 日本内科学会, 2006-01-01

著者名:

• Yoshita, Mitsuhiro
• Ishida, Chiho
• Yanase, Daisuke
• Yamada, Masahito

掲載情報:

Internal Medicine

ISSN:

0918-2918      

巻:

45

通号:

3

開始ページ:

159

終了ページ:

162

バージョン:

publisher

概要:

金沢大学医薬保健研究域医学系<br />Myasthenic symptoms and the echocardiographic findings of dilated cardiomyopathy are very rare in primary AL amyloidosis. We report a 59yearold man with dyspnea on effort and weakness after exercise. His electrocar … diogram showed ischemic heart disease and echocardiography indicated dilated cardiomyopathy. Muscle biopsy revealed amyloidosis with deposits of lambda light chainderived amyloid within the vessel wall. Treatment with PGE1 resulted in improvement of the myasthenic symptoms. This patient indicates that myasthenic symptoms and dilated cardiomyopathy would be a unique syndrome associated with systemic AL amyloidosis involving mainly the small vessels, i.e., AL amyloid angiopathy, in the skeletal muscles and myocardium vessels. 続きを見る

URL:

http://hdl.handle.net/2297/24040