IgG4-related tubulointerstitial nephritis and hepatic inflammatory pseudotumor without hypocomplementemia

IgG4-related tubulointerstitial nephritis and hepatic inflammatory pseudotumor without hypocomplementemia

フォーマット:

論文

責任表示:

Kim, Fae ; Yamada, Kazunori ; Inoue, Dai ; Nakajima, Kenichi ; Mizushima, Ichiro ; Kakuchi, Yasushi ; Fujii, Hiroshi ; Narumi, Kenta ; Matsumura, Masami ; Umehara, Hisanori ; Yamagishi, Masakazu ; Kawano, Mitsuhiro

言語:

英語

出版情報:

The Japanese Society of Internal Medicine = 日本内科学会, 2011-01-01

著者名:

掲載情報:

Internal Medicine

ISSN:

0918-2918

巻:

50

通号:

11

開始ページ:

1239

終了ページ:

1244

バージョン:

publisher

概要:

金沢大学附属病院リウマチ・膠原病内科<br />Immunoglobulin G4 (IgG4)-related tubulointerstitial nephritis (TIN) is often accompanied by autoimmune pancreatitis (AIP) or chronic sclerosing dacryoadenitis and sialoadenitis. However, IgG4-related TIN withou … t AIP or lacrimal and/or salivary gland lesions has not been well recognized. Here, we report a case of IgG4-related TIN associated with hepatic inflammatory pseudotumor without AIP or lacrimal and/or salivary gland lesions. A 58-year-old Japanese man with epigastralgia underwent contrast-enhanced computed tomography (CT), which revealed multiple low-density lesions in both kidneys and a low density hepatic mass. Laboratory tests showed an extremely high level of serum IgG4. Percutaneous renal and hepatic biopsies showed diffuse infiltration of lymphocytes and IgG4-positive plasma cells with fibrosis in both tissues. Two months after administration of oral prednisolone, both lesions decreased in size on follow-up CT, and the serum cre-atinine level also improved. No recurrence has been detected for two years with a maintenance dose of pred-nisolone. © 2011 The Japanese Society of Internal Medicine. 続きを見る

URL:

http://hdl.handle.net/2297/28339

タイトル・著者・出版者が同じ資料

詳細

主題:	Hepatic inflammatory pseudotumor; IgG4-related tubulointerstitial nephritis
受理日:	2011-01-01

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