A natural inter-genotypic (2b/1b) recombinant of hepatitis C virus in the Philippines

フォーマット:

論文

責任表示:

Kageyama, Seiji ; Agdamag, Dorothy M. ; Alesna, Evelyn T. ; Leaño, Prisca S. ; Heredia, Marie L. Anna ; Abellanosa-Tac-An, Ilya P. ; Jereza, Lourdes D. ; Tanimoto, Tomoaki ; Yamamura, Jun-ichi ; Ichimura, Hiroshi

言語:

英語

出版情報:

John Wiley & Sons, 2006-11-01

著者名:

Kageyama, Seiji

Agdamag, Dorothy M.

Alesna, Evelyn T.

Leaño, Prisca S.

Heredia, Marie L. Anna

Abellanosa-Tac-An, Ilya P.

Jereza, Lourdes D.

Tanimoto, Tomoaki

Yamamura, Jun-ichi

Ichimura, Hiroshi

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掲載情報:

Journal of Medical Virology

ISSN:

0146-6615      

巻:

78

通号:

11

開始ページ:

1423

終了ページ:

1428

概要:

金沢大学大学院医学系研究科感染症制御学<br />The prevalence study and the characterization of hepatitis C virus (HCV) was carried out in the Philippines and the sequence determination of the 5′-untranslated region (5′-UTR)-Core and the NS5B r … egions of HCV was carried out in this study. An HCV strain (SE-03-07-1689) collected in Metro Manila, Philippines, belonged to discordant subtypes, 2b and 1b in 5′-UTR-Core and NS5B regions, respectively. The 9.3 kb sequence of this strain including the entire open reading frame was compared with those of the reference strains retrieved from the HCV sequences database (GenBank/EMBL/DDBJ) and indicated a recombination event. The computation of the sequence similarity mapped a crossover point within the NS3 region. This is the second report on the inter-genotype recombinant of HCV and the third when an intra-genotype recombinant is included. This recombinant strain, SE-03-07-1689, is designated tentatively as RF3_2b/1b according to the suggestions used for the other two HCV recombinants. © 2006 Wiley-Liss, Inc. 続きを見る

URL:

http://hdl.handle.net/2297/2954