Is Estrogen Effective for Full-Thickness Cutaneous Wound Healing in Young Male Mice ?

Is Estrogen Effective for Full-Thickness Cutaneous Wound Healing in Young Male Mice ?

フォーマット:

論文

責任表示:

Nakajima, Yukari ; Eno, Yuka ; Hirata, Mariko ; Kobori, Sawako ; Sugiura, Ayano ; Takeuchi, Maiko ; Taniguchi, Miho ; Tanisaki, Megumi ; Hayashi, Asuka ; Hikishima, Keiko ; Matsuo, Naoki ; Wada, Natsumi ; Mukai, Kanae ; Murakado, Naoko ; Okuwa, Mayumi ; Nakatani, Toshio

言語:

英語

出版情報:

Health Management Publications, 2013-10-15

著者名:

掲載情報:

Wounds : a compendium of clinical research and practice

ISSN:

1044-7946

巻:

25

通号:

10

開始ページ:

278

終了ページ:

286

バージョン:

author

概要:

The aim of this study is to show the effects of estrogen upon its topical application on the wound healing process in young male mice. Fifty-six male mice aged 7 weeks old were divided into 4 groups: sham operation, castration, estrogen treatment after sham operation, and estrogen treatment after castration. Wound healing was observed daily until day 14 after wounding. Specimens were harvested on days 3, 7, 10, and 14, and stained to evaluate … reepithelialization, inflammation, contraction, and collagen accumulation. Wound healing periods of all groups were almost the same, although the concentration of serum estrogen in the estrogen-applied mice was very high, and that in the nonapplied groups was low. The numbers of macrophages in the castrated, estrogen-treated after sham operation, and estrogen-treated after castration groups were significantly decreased compared with that in the sham group in the inflammatory phase; however, the ratio of wound area in these groups did not decrease, and other histological data did not reveal any effects of estrogen. These results indicate that estrogen may show limited effectiveness for full-thickness cutaneous wound healing in young male mice, and decreased inflammation may not always be associated with decreased wound area. 続きを見る

URL:

http://hdl.handle.net/2297/35866

タイトル・著者・出版者が同じ資料

詳細

主題:	castration; cutaneous wound healing; estrogen; testosterone; young male mouse
受理日:	2013-10-15

類似資料:

1

2

3

4

5

6

7

8

9

10

11

12

1 論文 Effects of three types of Japanese honey on full-thickness wound in mice Nakajima, Yukari, Nakano, Yuki, Fuwano, Sono, Hayashi, Natsumi, Hiratoko, Yukiho, Kinoshita, Ayaka, Miyahara, Megumi, … Hindawi Publishing Corporation	7 論文 Evaluation of Indonesian and two types of Japanese honey on the acceleration of cutaneous wound healing: an experimental study in mice. Haryanto, Mukai, Kanae, Nakajima, Yukari, Okuwa, Mayumi, Cau, Kim Jiu, Sugama, Junko, Nakatani, Toshio, 向井, … Universitas 'Aisyiyah (UNISA) Yogyakarta
2 論文 Evaluation of the effects of a combination of Japanese honey and hydrocolloid dressing on cutaneous wound healing in male mice Mukai, Kanae, Koike, Miki, Nakamura, Saki, Kawaguchi, Yuka, Katagiri, Fumika, Nojiri, Saki, Yamada, Yuki, Miyajima, Eri, … Hindawi Publishing Corporation	8 論文 17β-Estradiol on Cutaneous Wound Healing in Protein-Malnourished Ovariectomized Female Mouse Model Mukai, Kanae, Komatsu, Emi, Nakajima, Yukari, Urai, Tamae, Nasruddin, Sugama, Junko, Nakatani, Toshio Public Library of Science
3 論文 The Relationship between Cutaneous Wounds Made on Obese Mice or Those with Decreased Body Weight and Serum Leptin Level Urai, Tamae, Haryanto, Mukai, Kanae, Matsushita, Tatsuhiko, Asano, Kimi, Nakajima, Yukari, Okuwa, Mayumi, Sugama, Junko, … Scientific Research Publishing	9 論文 Topical estrogen application to wounds promotes delayed cutaneous wound healing in 80-week-old female mice Mukai, Kanae, Komatsu, Emi, Nakajima, Yukari, Urai, Tamae, Nasruddin, Sugama, Junko, Nakatani, Toshio, 向井, … Public Library of Science
4 論文 Lymph Drainage during Wound Healing in a Hindlimb Lymphedema Mouse Model Komatsu, Emi, Nakajima, Yukari, Mukai, Kanae, Urai, Tamae, Asano, Kimi, Okuwa, Mayumi, Sugama, Junko, Nakatani, Toshio Mary Ann Liebert Inc.	10 論文 The effect of 17β-estradiol administration on cutaneous wound healing in 24-week ovariectomized female mice Mukai, Kanae, Nakajima, Yukari, Urai, Tamae, Komatsu, Emi, Takata, Kana, Miyasaka, Yuriko, Nasruddin, Sugama, Junko, … Hindawi Publishing Corporation
5 論文 Comparison of the Cutaneous Wound Healing of Ovariectomized Mouse at 12 Weeks with That of SHAM and Estrogen-Administered Mice Mukai, Kanae, Miyasaka, Yuriko, Takata, Kana, Urai, Tamae, Nakajima, Yukari, Komatsu, Emi, Sugama, Junko, Nakatani, … Hindawi Publishing Corporation	11 論文 Effectiveness of Indonesian Honey on the Acceleration of Cutaneous Wound Healing: An Experimental Study in Mice Haryanto, Urai, Tamae, Mukai, Kanae, Suriadi, Sugama, Junko, Nakatani, Toshio HMP Communications, LLC
6 論文 The effect of isoflavone-daidzein oral medication on cutaneous wound healing in female ovariectomized mice Mukai, Kanae, Nagasawa, Mari, Nakamura, Eri, Nishida, Natsuki, Hori, Ayaka, Yagi, Yukari, Yamagishi, Aya, Watanabe, Ai, … コ・メディカル形態機能学研究会	12 論文 Cold plasma on full-thickness cutaneous wound accelerates healing through promoting inflammation, re-epithelialization and wound contraction Nasruddin, Nakajima, Yukari, Mukai, Kanae, Rahayu, Heni Setyowati Esti, Nur, Muhammad, Ishijima, Tatsuo, Enomoto, … Elsevier