Insulin autoimmune syndrome caused by an adhesive skin patch containing loxoprofen-sodium

フォーマット:

論文

責任表示:

Okazaki-Sakai, Satoko ; Yoshimoto, Sachiko ; Yagi, Kunimasa ; Wakasugi, Takanobu ; Takeda, Yoshiyu ; Yamagishi, Masakazu

言語:

英語

出版情報:

Japanese Society of Internal Medicine = 日本内科学会, 2013-01-01

著者名:

Okazaki-Sakai, Satoko

Yoshimoto, Sachiko

Yagi, Kunimasa

Wakasugi, Takanobu

Takeda, Yoshiyu

Yamagishi, Masakazu

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掲載情報:

Internal Medicine

ISSN:

0918-2918      

巻:

52

通号:

21

開始ページ:

2447

終了ページ:

2451

バージョン:

author

概要:

A 62-year-old woman complained of repeated hypoglycemic events. A 75g oral glucose tolerance test (75 gOGTT) showed a marked increase in the plasma insulin level and impaired glucose tolerance. The patient exhibited a high titer of plasma anti-insulin autoantibodies. Her diagnosis was insulin autoimmune syndrome (IAS). Following the cessation of loxoprofen-sodium (LOXs), she experienced no further hypoglycemic episodes. However, the hypoglycemic attacks … recurred following the accidental readministration of LOXs in an adhesive skin patch. Considering the changes in the titer of anti-insulin autoantibodies, the repeated 75 gOGTT and the repeated Scatchard analysis, we determined LOXs to be the cause of the IAS and evaluated the characteristics of the autoantibodies. © 2013 by The Japanese Society of Internal Medicine. 続きを見る

URL:

http://hdl.handle.net/2297/36256