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Reversibility of the Pulmonary Function Based on the Partial Flow-volume Curve Predicts the Efficacy of Bronchodilator Therapy for Treating Chronic Cough
- フォーマット:
- 論文
- 責任表示:
- Nakade, Yusuke ; Fujimura, Masaki ; Ohkura, Noriyuki ; Nakata, Masako ; Nanbu, Yuko ; Oe, Hiroyasu ; Horita, Hiroshi ; Sakai, Yoshio ; Wada, Takashi
- 言語:
- 英語
- 出版情報:
- The Japanese Society of Internal Medicine 日本内科学会, 2013-01-01
- 著者名:
Nakade, Yusuke Fujimura, Masaki Ohkura, Noriyuki Nakata, Masako Nanbu, Yuko Oe, Hiroyasu Horita, Hiroshi Sakai, Yoshio Wada, Takashi - 掲載情報:
- Internal Medicine
- ISSN:
- 0918-2918
- 巻:
- 52
- 通号:
- 18
- 開始ページ:
- 2017
- 終了ページ:
- 2023
- バージョン:
- publisher
- 概要:
- Objective Partial expiratory flow-volume curves have the potential to detect mild bronchoconstriction because they are not affected by the modulatory effects of deep inspiration. The aim of this study was to investigate the relationship between the efficacy of bronchodilator therapy (BDT) in treating the cough and to assess the increase in the expiratory flow of the partial flow-volume curve at 40% above the residual volume level (PEF40) caused by treatment with a … short-acting beta-2 agonist (SABA) in patients with chronic nonproductive cough. Methods We measured the reversibility of PEF40 caused by a SABA in 42 patients with chronic nonproductive cough at visit 1 (day 0). The patients received BDT for six days. The visual analogue scale (VAS) was used to assess the efficacy of BDT in treating coughing at visit 2 (day 7) (0 mm, 'no cough;' 100 mm, 'no change in coughing'). Results Reversibility of the PEF40 was correlated (r=0.690, p<0.001) with the VAS score determined at visit 2 and was higher in the patients with cough variant asthma (CVA) (44.9±18.3%) than in those with atopic cough (13.4±10.4%) (p<0.01). Conclusion Reversibility of the PEF40 predicted the efficacy of BDT in patients with chronic nonproductive cough and helped to identify patients with CVA. 続きを見る
- URL:
- http://hdl.handle.net/2297/36474
類似資料:
金沢大学医薬保健研究域医学系 | |
Asian Association for the Study of Diabetes and Blackwell Publishing Asia Pty Ltd. / Wiley Open Access | |
Blackwell Publishing | |
5
論文
Bronchodilator-resistive cough in atopic patients: Bronchial reversibility and hyperresponsiveness
日本内科学会 = Japanese Society of Internal Medicine |
金沢大学医薬保健研究域医学系 |
Springer Verlag (Germany) |