Association between coefficients of variation of the R-R intervals on electrocardiograms and post-challenge hyperglycemia in patients with newly diagnosed type 2 diabetes

フォーマット:

論文

責任表示:

Nakade, Yusuke ; Takamura, Toshinari ; Sakurai, Masaru ; Misu, Hirofumi ; Nagata, Mitsuko ; Nanbu, Yuko ; Oe, Hiroyasu ; Takamura, Toshiji ; Sakai, Yoshio ; Kaneko, Shuichi ; Wada, Takashi

言語:

英語

出版情報:

Asian Association for the Study of Diabetes and Blackwell Publishing Asia Pty Ltd. / Wiley Open Access, 2011-08-01

著者名:

Nakade, Yusuke

Takamura, Toshinari

Sakurai, Masaru

Misu, Hirofumi

Nagata, Mitsuko

Nanbu, Yuko

Oe, Hiroyasu

Takamura, Toshiji

Sakai, Yoshio

Kaneko, Shuichi

Wada, Takashi

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掲載情報:

Journal of Diabetes Investigation

ISSN:

2040-1116      

巻:

2

通号:

4

開始ページ:

324

終了ページ:

327

バージョン:

publisher

概要:

The aim of the present study was to examine whether there is a relationship between autonomic function and post-challenge hyperglycemia in patients with type 2 diabetes. Subjects included 122 Japanese patients newly diagnosed with type 2 diabetes. Autonomic nerve function was assessed using coefficients of variation of the R-R intervals on electrocardiograms (CVRR). Unlike anthropometry, insulin secretion and insulin resistance, age (r =)0.209, P < … 0.021) and post-challenge plasma glucose at 120 min (PG120; r =)0.219, P < 0.015) were the only variables significantly correlated with CVRR. Age was not significantly correlated with PG120. In multiple regression analyses, CVRR Z-score, but not age, was significantly correlated with PG120. The present results suggest that autonomic function affects post-challenge blood glucose levels independently of age. © 2011 Asian Association for the Study of Diabetes and Blackwell Publishing Asia Pty Ltd. 続きを見る

URL:

http://hdl.handle.net/2297/36514