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Prevalence and risk factors of hepatocellular carcinoma in Japanese patients with primary biliary cirrhosis
- フォーマット:
- 論文
- 責任表示:
- Harada, Kenichi ; Nakanuma, Yasuni
- 言語:
- 英語
- 出版情報:
- Japan Society of Hepatology / Wiley, 2014-02-01
- 著者名:
- 掲載情報:
- Hepatology Research
- ISSN:
- 1386-6346
- 巻:
- 44
- 通号:
- 2
- 開始ページ:
- 133
- 終了ページ:
- 140
- バージョン:
- author
- 概要:
- Primary biliary cirrhosis (PBC) tends to affect females more than males. PBC selectively damages intrahepatic small bile ducts, particularly interlobular bile ducts. The clinical presentation of PBC has changed according to recent advances in clinicobiological diagnosis and improvements in therapeutic effects and prognosis. In particular, we encounter PBC patients with hepatocellular carcinoma (HCC), and the number of these patients appears to have increased. The … precise reason for the increased number of PBC patients with HCC in recent decades remains unknown, but recognizing the current status of carcinogenesis in PBC patients, identifying the associated clinicopathological risk factors and understanding how the pathogenesis of PBC is directly associated with HCC, is important. In this review, we summarize the data from two nationwide surveys undertaken in Japan as well as recent data from Japanese and international studies. © 2013 The Japan Society of Hepatology. 続きを見る
- URL:
- http://hdl.handle.net/2297/36986
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Intraductal papillary neoplasm of the bile duct in liver cirrhosis with hepatocellular carcinoma
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日本内科学会 = Japanese Society of Internal Medicine |
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Springer Science+Business Media | |
日本内科学会 = The Japanese Society of Internal Medicine |