Predictive factors for postoperative tachyarrhythmia after thoracoscopic esophagectomy and the usefulness of landiolol hydrochloride for its treatment

フォーマット:

論文

責任表示:

Okamoto, Koichi ; Ninomiya, Itasu ; Maruzen, Shogo ; Saito, Hiroto ; Tsukada, Tomoya ; Kinoshita, Jun ; Makino, Isamu ; Nakamura, Keishi ; Oyama, Katsunobu ; Miyashita, Tomoharu ; Tajima, Hidehiro ; Takamura, Hiroyuki ; Kitagawa, Hirohisa ; Fushida, Sachio ; Fujimura, Takashi ; Ohta, Tetsuo

言語:

英語

出版情報:

The Japan Esophageal Society, 日本食道学会 / Springer Japan, 2014-08-01

著者名:

Okamoto, Koichi

Ninomiya, Itasu

Maruzen, Shogo

Saito, Hiroto

Tsukada, Tomoya

Kinoshita, Jun

Makino, Isamu

Nakamura, Keishi

Oyama, Katsunobu

Miyashita, Tomoharu

Tajima, Hidehiro

Takamura, Hiroyuki

Kitagawa, Hirohisa

Fushida, Sachio

Fujimura, Takashi

Ohta, Tetsuo

続きを見る

掲載情報:

Esophagus

ISSN:

1612-9067      

巻:

11

通号:

2

開始ページ:

89

終了ページ:

98

バージョン:

publisher

概要:

Background: Tachyarrhythmia after esophagectomy is a severe complication that should not be underestimated because of its negative impact. The aims of this study were to clarify the cause and impact of postoperative tachyarrhythmia after thoracoscopic esophagectomy. Additionally, we analyzed the usefulness of landiolol administration for postoperative tachyarrhythmia. Methods: We evaluated the predictive factors for tachyarrhythmia onset after surgery and its … clinical impact in 127 patients who underwent thoracoscopic esophagectomy with extended lymphadenectomy. Moreover, we analyzed the efficacy of landiolol for postoperative tachyarrhythmia. Results: Tachyarrhythmia developed in 38 of the 127 patients. Multivariate analysis showed that advanced age, heart disease, and hyperlipidemia were associated with postoperative tachyarrhythmia. Hyponatremia, hypoalbuminemia, and leukocytosis on postoperative day 3 were significantly associated with tachyarrhythmia onset. The incidence of all complications and respiratory complications, including pneumonia, was significantly higher in patients with than in those without tachyarrhythmia. The mortality rate in the tachyarrhythmia group tended to be higher than that in the nontachyarrhythmia group. Landiolol as a treatment for tachyarrhythmia immediately decreased heart rate and safely reduced subsequent respiratory complications. Conclusion: In elderly patients with cardiac disease or hyperlipidemia, surgeons should be alert for the occurrence of tachyarrhythmia after esophagectomy. Postoperative tachyarrhythmia is a marker of morbidities with particular emphasis on respiratory complications. However, it can be adequately managed by landiolol, resulting in fewer respiratory complications. Landiolol might be a safe and convenient agent for managing postoperative tachyarrhythmia after thoracoscopic esophagectomy, resulting in lower mortality and morbidity rates. © 2013 The Japan Esophageal Society and Springer. 続きを見る

URL:

http://hdl.handle.net/2297/37574