Reactions of 1-methoxy-3-(2-nitrovinyl)indole with nucleophiles: An interesting solvent effect and a novel preparation of 3-substituted 1-methoxyindoles

Reactions of 1-methoxy-3-(2-nitrovinyl)indole with nucleophiles: An interesting solvent effect and a novel preparation of 3-substituted 1-methoxyindoles

フォーマット:

論文

責任表示:

Yamada, Koji ; Yamada, Fumio ; Somei, Masanori

言語:

英語

出版情報:

日本複素環化学研究所, 2002-07-01

著者名:

掲載情報:

Heterocycles

巻:

57

通号:

7

開始ページ:

1231

終了ページ:

1234

バージョン:

publisher

概要:

金沢大学大学院自然科学研究科生理活性物質科学<br />Nucleophiles react with 1-methoxy-3-(2-nitrovinyl)indole (3) at the 2-position regioselectively in a dipolar aprotic solvent (DMF or HMPA), while in THF they undergo Michael addition to the β-carbon of … nitrovinyl side chain. Depending on bases employed, the resultant Michael addition products (6d, 10, and 11) are found to undergo interesting cyclizations to give novel 3-substituted 1-methoxyindoles (7, 9, and 12). 続きを見る

URL:

http://hdl.handle.net/2297/4371

タイトル・著者・出版者が同じ資料

詳細

主題:	1 methoxy 3 (2 nitrovinyl)indole; indole derivative; solvent
受理日:	2002-07-01

類似資料:

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1 論文 Solvent effect on the reaction of 1-methoxy-3-(2-nitrovinyl)indole with nucleophiles Yamada, Koji, Izumi, Tomoyuki, Yamada, Fumio, Somei, Masanori 日本複素環化学研究所	7 論文 Introduction of nucleophiles or ethyl group to the indole nucleus through nucleophilic substitution and/or radical reactions of 1-methoxyindole-3- and … Yamada, Fumio, Fukui, Yoshikazu, Shinmyo, Daisuke, Somei, Masanori 日本複素環化学研究所
2 論文 Nucleophilic substitution reaction of 1-methoxy-6-nitro-indole Yamada, Koji, Kawasaki, Toshiya, Fujita, Tomomi, Somei, Masanori 日本複素環化学研究所	8 論文 Nucleophilic substitution reactions of 1-methoxy-6-nitroindole-3-carbaldehyde 1 Yamada, Koji, Yamada, Fumio, Shiraishi, Takei, Tomioka, Saori, Somei, Masanori 日本複素環化学研究所
3 論文 Synthesis of 3a-(indol-3-yl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole core of leptosins D-F based on nucleophilic substitution reaction on indole nucleus Yamada, Fumio, Goto, Aya, Somei, Masanori 日本複素環化学研究所	9 論文 Nucleophilic substitution reaction of 3-acetyl-1-methoxyindole and its application for the synthesis of novel 2-substituted methyl 2,3-dihydro-1- … Somei, Masanori, Nakajou, Masahiro, Teramoto, Tsuyoshi, Tanimoto, Asuka, Yamada, Fumio 日本複素環化学研究所
4 論文 Nucleophilic substitution reaction on the nitrogen of indole nucleus: Formation of 1-(indol-3-yl)indoles upon reaction of 1-hydroxyindoles with indole in formic … Somei, Masanori, Yamada, Fumio, Hayashi, Toshikatsu, Goto, Aya, Saga, Yoshitomo 日本複素環化学研究所	10 論文 Nucleophilic substitution reaction in indole chemistry: A synthesis of novel 7β-substituted yohimbine and 4aα-substituted 1,2,3,4-tetrahydro-β-carboline … Yoshino, Katsumasa, Yamada, Fumio, Somei, Masanori Japan Institute of Heterocyclic Chemistry = 日本複素環化学研究所
5 論文 Nucleophilic substitution reaction in indole chemistry: 1-methoxy-6-nitroindole-3-carbaldehyde as a versatile building block for 2,3,6-trisubstituted indoles Yamada, Koji, Yamada, Fumio, Shiraishi, Takei, Tomioka, Saori, Somei, Masanori The Japan Institute of Heterocyclic Chemistry / Elsevier	11 論文 Short step syntheses of indolo[2,3-a]carbazoles carrying an alkyl, allyl, or a glycosyl group at the 11-position and a novel … Somei, Masanori, Yamada, Fumio, Kato, Jun, Suzuki, Yoshiaki, Ueda, Yoshinori 日本複素環化学研究所
6 論文 Nucleophilic Substitution Reaction in Indole Chemistry: 1-Methoxy-6-nitroindole-3-carbaldehyde as a Versatile Building Block for 2,3,6-Trisubstituted Indoles Yamada, Koji, Yamada, Fumio, Shiraishi, Takei, Tomioka, Saori, Somei, Masanori Japan Institute of Heterocyclic Chemistry = 日本複素環化学研究所	12 論文 Nucleophilic substitution reaction of 1-methoxyindole-3-carbaldehyde Yamada, Fumio, Shinmyo, Daisuke, Nakajou, Masahiro, Somei, Masanori Japan Institute of Heterocyclic Chemistry 有機合成化学協会 / Elsevier