Nucleophilic substitution reaction at the 1-position of 1-hydroxytryptamine and -tryptophan derivatives

Nucleophilic substitution reaction at the 1-position of 1-hydroxytryptamine and -tryptophan derivatives

フォーマット:

論文

責任表示:

Yamada, Fumio ; Goto, Aya ; Peng, Wu ; Hayashi, Toshikatsu ; Saga, Yoshitomo ; Somei, Masanori

言語:

英語

出版情報:

日本複素環化学研究所, 2003-12-31

著者名:

掲載情報:

Heterocycles

巻:

61

開始ページ:

163

終了ページ:

172

バージョン:

publisher

概要:

金沢大学大学院自然科学研究科生理活性物質科学<br />金沢大学薬学部<br />A novel nucleophilic substitution reaction at the 1-position of indole nucleus was discovered by reacting 1-hydroxytryptamine and -tryptophan derivatives with indoles in 85% formic acid y … ielding 1-(indol-3-yl)indoles. Their structures were determined by X-Ray crystallographic analysis and chemical correlations. An SN2 mechanism on the indole nitrogen (1-position) is proposed. 続きを見る

URL:

http://hdl.handle.net/2297/4378

タイトル・著者・出版者が同じ資料

詳細

主題:	1 hydroxytryptamine derivative; substitution reaction; tryptamine derivative; tryptophan derivative
受理日:	2003-12-31

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1 論文 Nucleophilic substitution reaction on the nitrogen of indole nucleus : A novel synthesis of 1-aryltrryptamines Hayashi, Toshikatsu, Peng, Wu, Nakai, Yu-ya, Yamada, Koji, Somei, Masanori 日本複素環化学研究所	7 論文 Nucleophilic substitution reaction of N-2-(1-hydroxyindol-3-yl)ethylindole-3-acetamide and -1-hydroxyindole-3-acetamide Nakai, Yu-ya, Goto, Aya, Yamada, Fumio, Somei, Masanori 日本複素環化学研究所
2 論文 Nucleophilic substitution reaction on the nitrogen of indole nucleus: Formation of 1-(indol-3-yl)indoles upon reaction of 1-hydroxyindoles with indole in formic … Somei, Masanori, Yamada, Fumio, Hayashi, Toshikatsu, Goto, Aya, Saga, Yoshitomo 日本複素環化学研究所	8 論文 Reactions of 1-hydroxyindoles with p-toluenesulfonyl chloride and p-toluenesulfonic acid Somei, Masanori, Yamada, Fumio, Goto, Aya, Hayashi, Masumi, Hasegawa, Masakazu 日本複素環化学研究所
3 論文 Nucleophilic substitution reactions of 1-methoxy-6-nitroindole-3-carbaldehyde 1 Yamada, Koji, Yamada, Fumio, Shiraishi, Takei, Tomioka, Saori, Somei, Masanori 日本複素環化学研究所	9 論文 Nucleophilic substitution reactions on indole nucleus: Formation of (3a,8a-cis)-1,2,3,3a,8,8a-hexahydropyrrolo-[2,3-b]indoles having a substituent at the … Yamada, Fumio, Goto, Aya, Hasegawa, Masakazu, Kobayashi, Kensuke, Somei, Masanori, 山田, 文夫, 染井, 正徳 Japan Institute of Heterocyclic Chemistry
4 論文 A novel methodology for preparing 5-chloro- and 5-bromotryptamines and tryptophans, and its application to the synthesis of (±)-bromochelonin B Hasegawa, Masakazu, Yamada, Koji, Nagahama, Yoshiyuki, Somei, Masanori 日本複素環化学研究所	10 論文 Nucleophilic substitution reaction in indole chemistry: A synthesis of novel 7β-substituted yohimbine and 4aα-substituted 1,2,3,4-tetrahydro-β-carboline … Yoshino, Katsumasa, Yamada, Fumio, Somei, Masanori Japan Institute of Heterocyclic Chemistry = 日本複素環化学研究所
5 論文 Nucleophilic substitution reaction of 1-hydroxytryptophan and 1-hydroxytryptamine derivatives regioselective syntheses of 5-substituted derivatives of … Somei, Masanori, Fukui, Yoshikazu 日本複素環化学研究所	11 論文 The chemistry of 1-hydroxyindole derivatives : nucleophilic substitution reactions on indole nucleus Somei, Masanori, Kawasaki, Toshiya, Fukui, Yoshikazu, Yamada, Fumio, Kobayashi, Tetsuya, Aoyama, Harumi, Shinmyo, … 日本複素環化学研究所
6 論文 Synthesis of 3a-(indol-3-yl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole core of leptosins D-F based on nucleophilic substitution reaction on indole nucleus Yamada, Fumio, Goto, Aya, Somei, Masanori 日本複素環化学研究所	12 論文 Syntheses of wasabi phytoalexin (methyl 1-methoxyindole-3-carboxylate) and its 5-iodo derivative, and their nucleophilic substitution reactions Somei, Masanori, Tanimoto, Asuka, Orita, Hitomi, Yamada, Fumio, Ohta, Toshiharu 日本複素環化学研究所