Impact of Distal Protection with Filter-Type Device on Long-term Outcome after Percutaneous Coronary Intervention for Acute Myocardial Infarction: Clinical Results with Filtrap®.

フォーマット:

論文

責任表示:

Teramoto, Ryota ; Sakata, Kenji ; Miwa, Kenji ; Matsubara, Takao ; Yasuda, Toshihiko ; Inoue, Masaru ; Okada, Hirofumi ; Kanaya, Honin ; Kawashiri, Masa-aki ; Yamagishi, Masakazu ; Hayashi, Kenshi ; 寺本, 了太 ; 坂田, 憲治 ; 川尻, 剛照 ; 山岸, 正和 ; 林, 研至

言語:

英語

出版情報:

Japan Atherosclerosis Society = 日本動脈硬化学会, 2016-12-01

著者名:

Teramoto, Ryota

Sakata, Kenji

Miwa, Kenji

Matsubara, Takao

Yasuda, Toshihiko

Inoue, Masaru

Okada, Hirofumi

Kanaya, Honin

Kawashiri, Masa-aki

Yamagishi, Masakazu

Hayashi, Kenshi

寺本, 了太

坂田, 憲治

川尻, 剛照

山岸, 正和

林, 研至

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掲載情報:

Journal of Atherosclerosis and Thrombosis

ISSN:

1340-3478      

巻:

23

通号:

12

開始ページ:

1313

終了ページ:

1323

バージョン:

publisher

概要:

Aim: Although distal embolization during percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) deteriorates cardiac function, whether distal protection (DP) can improve prognosis is still controversial. We investiga … ted whether a filter-type DP device, Filtrap®, could improve long-term outcomes after PCI for AMI. Method: We studied 164 patients (130 men, mean age: 65.7 years) who underwent PCI. Patients were divided into two groups based on the use of Filtrap®. The occurrence of congestive heart failure (CHF) and major adverse cardiac events (MACE) defined as cardiac death, recurrent AMI, and target vessel revascularization were compared. Result: Between DP (n=53, 41 men, mean age: 65.5 years) and non-DP (n=111, 89 men, mean age: 65.8 years) groups, although there was significantly greater plaque area in the DP group than in the non-DP group, there were no significant differences in coronary reperfusion flow after PCI. Interestingly, patients with CHF in the non-DP group exhibited a higher CK level than those in the DP group. During a 2-year follow-up period, cumulative CHF was significantly lower in the DP group than in the non-DP group (log-rank p=0.018), and there was no significant difference in the MACE rate (log-rank p=0.238). The use of DP device could not predict MACE, but could predict CHF by multivariate analysis (odds ratio=0.099, 95% CI: 0.02–0.42, p=0.005). Conclusion: These results demonstrate that favorable clinical outcomes could be achieved by the filter-type DP device in AMI, particularly in patients with CHF.<br />出版者照会後に全文公開 続きを見る

URL:

http://hdl.handle.net/2297/48550