※一部利用できない機能があります
Purines. LXII. Both Enantiomers of N^6-(1,3-Dimetyl-2-butenyl)adenine and Their 9-β-D-Ribofuranosides : Synthesis and Cytokinin Activity
- フォーマット:
- 論文
- 責任表示:
- Fujii, Tozo ; Ohba, Masashi ; Kawamura, Hitoshi ; Nakashio, Yoshiyuki ; Honda, Kei ; Matsubara, Satoshi
- 言語:
- 英語
- 出版情報:
- 日本薬学会, 1994-05-15
- 著者名:
Fujii, Tozo Ohba, Masashi Kawamura, Hitoshi Nakashio, Yoshiyuki Honda, Kei Matsubara, Satoshi - 掲載情報:
- Chemical & pharmaceutical bulletin
- ISSN:
- 0009-2363
- 巻:
- 42
- 通号:
- 5
- 開始ページ:
- 1045
- 終了ページ:
- 1049
- バージョン:
- publisher
- 概要:
- Both enantiomers [(1'R)-6 and (1'S)-6] of N6-(1,3-dimethyl-2- butenyl)adenine and their 9-β-D-ribofuranosides [(1''R)-16 and (1''S)-16] have been synthesized for the first time from both enantiomers of ala … nine (15) in nine steps. These aglycones and nucleosides, together with N6-(3- methyl-2-butenyl)adenine (5) and its 9-β-D-ribofuranoside (18) as well as 9- β-D-ribofuranosyl-cis-zeatin (20) and 9-(2-deoxy-β-D-ribofuranosyl)-cis- zeatin (19), were tested for cytokinin activity in the tobacco callus bioassay. The order of their activity was 5> (1'R)-6 > (1''R)-16≃18>(1'S)- 6>(1''S)-16>20>19. The bioassay results are compared with those obtained previously for the derivatives modified analogously in the N6-substituent in the cis- and trans-zeatin series. 続きを見る
- URL:
- http://hdl.handle.net/2297/7617