Lactams. XIX. The Alkaline Ferricyanide Oxidation of 1,3-Disubstituted Pyridinium Salts : Effects of Branched Alkyl Groups at the 3-Position

フォーマット:

論文

責任表示:

Fujii, Tozo ; Hiraga, Takashi ; Ohba, Masashi

言語:

英語

出版情報:

日本薬学会, 1981-09-25

著者名:

• Fujii, Tozo
• Hiraga, Takashi
• Ohba, Masashi

掲載情報:

Chemical & pharmaceutical bulletin

ISSN:

0009-2363      

巻:

29

通号:

9

開始ページ:

2503

終了ページ:

2508

バージョン:

publisher

概要:

In the oxidation of 3-substituted 1-methylpyridinium salts (type III) with potassium ferricyanide and KOH at 32℃, the isopropyl and the tert-butyl group at the 3-position were found to orient oxidation to both the 2-(type IV) and the 6-posi … tion (type V) in ratios of 71 : 29 and 14 : 86,respectively. In the oxidation of the 1-methyl-3-tert-butyl-pyridinium salt (IIIl), replacement of the 1-methyl group by an aralkyl group along the series benzyl, phenethyl, and 3,4-dimethoxyphenethyl decreased the extent of the 2-pyridone formation along the series. 続きを見る

URL:

http://hdl.handle.net/2297/7625