金沢大学附属図書館 OPAC plus

概要: To explore the impact of geographical location, built environment, public transportation service and individual socioeco … nomic attributes on commuting carbon dioxide (CO2) emissions, a survey was conducted in 27 residential compounds of Shanghai in 2016. In this paper, commuting distance was calculated according to a Baidu map application programming interface (API). CO2 emissions were calculated based on the mode used in each segment of commuting and distance travelled. Through the use of a multiple linear regression model, factors of personal socioeconomic attributes, including gender, occupation and apartment area, were significant to commuting CO2 emissions. In terms of the public transport service, the distance from compounds to the nearest metro station was found to be a significant factor on CO2 emissions, whereas the built environment, such as parking space and employment density, had a weak impact in our study. In addition, even when living near a metro station, the top 20% of travellers’ CO2 emissions can account for approximately 80% of the total CO2 emissions. Hence, policies to reduce those people’s commuting CO2 emissions are worth further exploring. 続きを見る

概要: 金沢大学疾患モデル総合研究センター<br />Leukocyte cell-derived chemotaxin 2 (LECT2) is a hepatokine that causes skeletal muscle insulin r … esistance. The circulating levels of LECT2 are a possible biomarker that can predict weight cycling because they reflect liver fat and precede the onset of weight loss or gain. Herein, to clarify the dynamics of this rapid change in serum LECT2 levels, we investigated the in vivo kinetics of LECT2, including its plasma half-life and tissue distribution, by injecting 125I-labelled LECT2 into ICR mice and radioactivity tracing. The injected LECT2 was eliminated from the bloodstream within 10 min (approximate half-life, 5 min). In the kidneys, the radioactivity accumulated within 10 min after injection and declined thereafter. Conversely, the radioactivity in urine increased after 30 min of injection, indicating that LECT2 is mainly excreted by the kidneys into the urine. Finally, LECT2 accumulated in the skeletal muscle and liver until 30 min and 2 min after injection, respectively. LECT2 accumulation was not observed in the adipose tissue. These findings are in agreement with LECT2 action on the skeletal muscle. The present study indicates that LECT2 is a rapid-turnover protein, which renders the circulating level of LECT2 a useful rapid-response biomarker to predict body weight alterations. © 2020, The Author(s).<br />CC-BY 4.0 続きを見る

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