1.

論文
論文
1. Selective estrogen receptor modulator raloxifene-associated aggravation of nonalcoholic steatohepatitis.
Takamura, Toshinari ; Shimizu, Akiko ; Komura, Takuya ; Ando, Hitoshi ; Zen, Yoh ; Minato, Hiroshi ; Matsushita, Eiki ; Kaneko, Shuichi
出版情報: Internal Medicine.  46  pp.579-581,  2007-05-01.  日本内科学会
URL: http://hdl.handle.net/2297/6609
概要: 金沢大学大学院医学系研究科環境社会医学<br />A 53-year-old postmenopausal woman, who had a family history of cryptogenic liver cirrhosis, wa … s diagnosed with osteoporosis, and started on the selective estrogen receptor modulator (SERM) raloxifene 60 mg/day orally. She developed marked liver dysfunction. Her body mass index (BNU) was 26.5. Her blood chemistry indicated AST 342 IU/L, ALT 356 IU/L, and hyaluronic acid 255 ng/mL. An oral glucose tolerance test showed impaired glucose tolerance with marked insulin resistance. Histologically, we diagnosed this case as having pre-cirrhotic nonalcoholic steatohepatitis (NASH). This is the first histologically confirmed case of NASH that was aggravated by raloxifene. © 2007 The Japanese Society of Internal Medicine. 続きを見る
2.

論文
論文
2. Abnormal liver function tests and metabolic syndrome - Is fatty liver related to risks for atherosclerosis beyond obesity?
Sakurai, Masaru ; Takamura, Toshinari ; Miura, Katsuyuki ; Kaneko, Shuichi ; Nakagawa, Hideaki
出版情報: Internal Medicine.  48  pp.1573-1574,  2009-01-01.  Japanese Society of Internal Medicine = 日本内科学会
URL: http://hdl.handle.net/2297/19772
概要: 金沢大学医薬保健研究域医学系