Impact of body mass index on in-hospital outcomes after percutaneous coronary intervention for ST segment elevation acute myocardial infarction.

フォーマット:

論文

責任表示:

Kosuge, Masami ; Kimura, Kazuo ; Kojima, Sunao ; Sakamoto, Tomohiro ; Ishihara, Masaharu ; Asada, Yujiro ; Tei, Chuwa ; Miyazaki, Shunichi ; Sonoda, Masahiro ; Tsuchihashi, Kazufumi ; Yamagishi, Masakazu ; Shirai, Mutsunori ; Hiraoka, Hisatoyo ; Honda, Takashi ; Ogata, Yasuhiro ; Ogawa, Hisao ; The Japanese Acute Coronary Syndrome Study (JACSS) Investigators ; 山岸, 正和

言語:

英語

出版情報:

Japanese Circulation Society = 日本循環器学会, 2008-03-25

著者名:

Kosuge, Masami

Kimura, Kazuo

Kojima, Sunao

Sakamoto, Tomohiro

Ishihara, Masaharu

Asada, Yujiro

Tei, Chuwa

Miyazaki, Shunichi

Sonoda, Masahiro

Tsuchihashi, Kazufumi

Yamagishi, Masakazu

Shirai, Mutsunori

Hiraoka, Hisatoyo

Honda, Takashi

Ogata, Yasuhiro

Ogawa, Hisao

The Japanese Acute Coronary Syndrome Study (JACSS) Investigators

山岸, 正和

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掲載情報:

Circulation journal

ISSN:

1346-9843      

巻:

72

通号:

4

開始ページ:

521

終了ページ:

525

バージョン:

publisher

概要:

Background The impact of body mass index (BMI) on outcomes after primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) remains unclear. Methods and Results A total of 3,076 patients undergoing PCI for AMI wi … thin 48 h after symptom onset were studied. Patients were divided into 4 groups according to baseline BMI: lean (<20 kg/m2), normal weight (20.0-24.9 kg/m2), overweight (25.0-29.9 kg/m2) and obese (≥30.0 kg/m2). Obese patients were younger and had a higher frequency of diabetes mellitus, hyperlipidemia, hypertension and smoking. Lean patients were older, usually women and had a lower frequency of the aforementioned risk factors. Killip class on admission, renal insufficiency, and final Thrombolysis In Myocardial Infarction (TIMI) flow grade did not differ among the 4 groups. In lean, normal weight, overweight and obese patients, in-hospital mortality was 9.2%, 4.4%, 2.5% and 1.8%, respectively (p<0.01). Multivariate analysis showed that compared with normal weight patients, odds ratios for in-hospital death in lean, overweight and obese patients were 1.92, 0.79 and 0.40, respectively (p=NS). Independent predictors were age, Killip class on admission, renal insufficiency and final TIMI flow grade. Conclusion BMI itself had no impact on in-hospital mortality in patients undergoing primary PCI for AMI. The phenomenon `obesity paradox' may be explained by the fact that obese patients were younger at presentation. (Circ J 2008; 72: 521 - 525)<br />出版者照会後に全文公開 続きを見る

URL:

http://hdl.handle.net/2297/48507