1.

論文
論文
1. Nucleophilic substitution reaction on the nitrogen of indole nucleus : A novel synthesis of 1-aryltrryptamines
Hayashi, Toshikatsu ; Peng, Wu ; Nakai, Yu-ya ; Yamada, Koji ; Somei, Masanori
出版情報: Heterocycles.  57  pp.421-424,  2002-03-01.  日本複素環化学研究所
URL: http://hdl.handle.net/2297/4370
概要: 金沢大学大学院自然科学研究科生理活性物質科学<br />1-Hydroxytryptamine derivatives undergo nucleophilic substitution reaction on the indole nit … rogen (Na) as a general reaction by the treatment with acid, providing a novel synthetic method for 1-aryltryptamines. Depending on the structures of nucleophiles, 5- and 7-substituted tryptamines can also be produced in addition to the 1-aryltryptamines. 続きを見る
2.

論文
論文
2. Preparation of 7-substituted 4,5-dihydro-7H-pyrano[3,4-c]-isoxazole derivatives
Yamada, Koji ; Yamada, Fumio ; Somei, Masanori
出版情報: Heterocycles.  59  pp.685-690,  2002-03-01.  日本複素環化学研究所
URL: http://hdl.handle.net/2297/4374
概要: 金沢大学大学院自然科学研究科生理活性物質科学<br />1-Hydroxytryptamine derivatives undergo nucleophilic substitution reaction on the indole nit … rogen (Na) as a general reaction by the treatment with acid, providing a novel synthetic method for 1-aryltryptamines. Depending on the structures of nucleophiles, 5- and 7-substituted tryptamines can also be produced in addition to the 1-aryltryptamines.<br />An easy approach to 7-substituted 4,5-dihydro-7H-pyrano[3,4-c]-isoxazole derivatives (3a-b and 6a-d) is described by the reaction of 2-aryl substituted 1-nitro-3-oxa-6-heptynes (2, 5a and 5b) with n-BuLi, followed by treatment with acetic anhydride. 続きを見る
3.

論文
論文
3. A novel preparation of 3-hydroxy-3H-indole-3-ethanamines and -3H-indole-3-acetamides having either a 4-morpholinyl or 1-pyrrolidinyl group at the 2-position
Hayashi, Toshikatsu ; Nakai, Yu-ya ; Yamada, Fumio ; Somei, Masanori
出版情報: Heterocycles.  62  pp.437-444,  2004-01-01.  日本複素環化学研究所
URL: http://hdl.handle.net/2297/4379
概要: 金沢大学大学院自然科学研究科生理活性物質科学<br />金沢大学薬学部<br />A novel synthetic method is discovered for 3-hydroxy-3H-indole-3-ethanamines an … d -3H-indole-3-acetamides having either a 4-morpholinyl or 1-pyrrolidinyl group at the 2-position by reacting the corresponding 1-hydroxyindoles with enamines in the presence of tosyl or mesyl chloride. A plausible mechanism is proposed. 続きを見る
4.

論文
論文
4. Three new synthetic methods for the 1,2,3,3a,8,8a-hexa-hydropyrrolo[2,3-b] indoles having an alkoxy group at the 3a-position
Iwaki, Takako ; Yamada, Fumio ; Funaki, Shiho ; Somei, Masanori
出版情報: Heterocycles.  65  pp.1811-1815,  2005-01-01.  日本複素環化学研究所
URL: http://hdl.handle.net/2297/4382
概要: 金沢大学大学院自然科学研究科生理活性物質科学<br />金沢大学薬学部<br />Three methods have been newly developed for the synthesis of 1,2,3,3a,8,8a-hexa … hydropyrrolo[2,3-b]indoles. Employing them, 3a-chloro-, 3a-bromo-, 3a-hydroxy-, and various 3a-alkoxy-1,2,3,3a,8,8a-hexahydropyrrolo[2, 3-b]indoles are now readily available. 続きを見る