Nucleophilic substitution reaction in indole chemistry: 1-methoxy-6-nitroindole-3-carbaldehyde as a versatile building block for 2,3,6-trisubstituted indoles

Nucleophilic substitution reaction in indole chemistry: 1-methoxy-6-nitroindole-3-carbaldehyde as a versatile building block for 2,3,6-trisubstituted indoles

フォーマット:

論文

責任表示:

Yamada, Koji ; Yamada, Fumio ; Shiraishi, Takei ; Tomioka, Saori ; Somei, Masanori

言語:

英語

出版情報:

The Japan Institute of Heterocyclic Chemistry / Elsevier, 2009-01-01

著者名:

掲載情報:

Heterocycles

ISSN:

0385-5414

巻:

77

通号:

2

開始ページ:

971

終了ページ:

982

バージョン:

author

概要:

1-Methoxy-6-nitroindole-3-carbaldehyde is proved to be a versatile electrophile and reacts regioselectively at the 2-position with various types of nucleophiles providing 2,3,6-trisubstituted indole derivatives. The reaction is applicable for the preparation of a novel pyrimido[1,2-a]indole derivative. © 2009 The Japan Institute of Heterocyclic Chemistry All rights reserved.

URL:

http://hdl.handle.net/2297/25290

タイトル・著者・出版者が同じ資料

詳細

主題:	1-Methoxy-6-nitroindole- 3-carbaldehyde; 1-Methoxyindole; 2-Substituted Indole; Nucleophilic Substitution Reaction; Pyrimido[1,2-a]indole
受理日:	2009-01-01

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1 論文 Nucleophilic Substitution Reaction in Indole Chemistry: 1-Methoxy-6-nitroindole-3-carbaldehyde as a Versatile Building Block for 2,3,6-Trisubstituted Indoles Yamada, Koji, Yamada, Fumio, Shiraishi, Takei, Tomioka, Saori, Somei, Masanori Japan Institute of Heterocyclic Chemistry = 日本複素環化学研究所	7 論文 Nucleophilic substitution reaction in indole chemistry: A synthesis of novel 7β-substituted yohimbine and 4aα-substituted 1,2,3,4-tetrahydro-β-carboline … Yoshino, Katsumasa, Yamada, Fumio, Somei, Masanori Japan Institute of Heterocyclic Chemistry = 日本複素環化学研究所
2 論文 Nucleophilic substitution reactions of 1-methoxy-6-nitroindole-3-carbaldehyde 1 Yamada, Koji, Yamada, Fumio, Shiraishi, Takei, Tomioka, Saori, Somei, Masanori 日本複素環化学研究所	8 論文 Solvent effect on the reaction of 1-methoxy-3-(2-nitrovinyl)indole with nucleophiles Yamada, Koji, Izumi, Tomoyuki, Yamada, Fumio, Somei, Masanori 日本複素環化学研究所
3 論文 Novel syntheses of 1-hydroxy-6- and -5-nitroindole-3-carbaldehydes, and their derivatives as daikon-phytoalexin analogs Yamada, Koji, Tomioka, Saori, Tanizawa, Noriko, Somei, Masanori 日本複素環化学研究所	9 論文 The Chemistry of Indoles. CVII. A Novel Synthesis of 3, 4, 5, 6-Tetrahydro-7-hydroxy-1H-azepino[5, 4, 3-cd]indoles and a New Finding on Pictet-Spengler Reaction Somei, Masanori, Teranishi, Sakiko, Yamada, Koji, Yamada, Fumio Pharmaceutical Society of Japan = 日本薬学会
4 論文 Nucleophilic substitution reaction of 1-methoxy-6-nitro-indole Yamada, Koji, Kawasaki, Toshiya, Fujita, Tomomi, Somei, Masanori 日本複素環化学研究所	10 論文 Nucleophilic substitution reaction on the nitrogen of indole nucleus: Formation of 1-(indol-3-yl)indoles upon reaction of 1-hydroxyindoles with indole in formic … Somei, Masanori, Yamada, Fumio, Hayashi, Toshikatsu, Goto, Aya, Saga, Yoshitomo 日本複素環化学研究所
5 論文 Reactions of 1-methoxy-3-(2-nitrovinyl)indole with nucleophiles: An interesting solvent effect and a novel preparation of 3-substituted 1-methoxyindoles Yamada, Koji, Yamada, Fumio, Somei, Masanori 日本複素環化学研究所	11 論文 The chemistry of 1-hydroxyindole derivatives : nucleophilic substitution reactions on indole nucleus Somei, Masanori, Kawasaki, Toshiya, Fukui, Yoshikazu, Yamada, Fumio, Kobayashi, Tetsuya, Aoyama, Harumi, Shinmyo, … 日本複素環化学研究所
6 論文 Nucleophilic substitution reaction of 1-methoxyindole-3-carbaldehyde Yamada, Fumio, Shinmyo, Daisuke, Nakajou, Masahiro, Somei, Masanori Japan Institute of Heterocyclic Chemistry 有機合成化学協会 / Elsevier	12 論文 Synthesis of 3a-(indol-3-yl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole core of leptosins D-F based on nucleophilic substitution reaction on indole nucleus Yamada, Fumio, Goto, Aya, Somei, Masanori 日本複素環化学研究所