Androgen replacement therapy for cancer-related symptoms in male advanced cancer patients: Study protocol for a randomised prospective trial (ARTFORM study)

Androgen replacement therapy for cancer-related symptoms in male advanced cancer patients: Study protocol for a randomised prospective trial (ARTFORM study)

フォーマット:

論文

責任表示:

Izumi, Kouji ; Shigehara, Kazuyoshi ; Nohara, Takahiro ; Narimoto, Kazutaka ; Kadono, Yoshifumi ; Nanjo, Shigeki ; Yamada, Tadaaki ; Ohtsubo, Koushiro ; Yano, Seiji ; Mizokami, Atsushi ; 泉, 浩二 ; 重原, 一慶 ; 野原, 隆弘 ; 角野, 佳史 ; 南條, 成輝 ; 山田, 忠明 ; 大坪, 公士郎 ; 矢野, 聖二 ; 溝上, 敦

言語:

英語

出版情報:

The University of Tokushima Faculty of Medicine, 2017

著者名:

掲載情報:

Journal of Medical Investigation

ISSN:

1343-1420

巻:

64

通号:

3-4

開始ページ:

202

終了ページ:

204

バージョン:

publisher

概要:

金沢大学附属病院泌尿器科<br />Recent studies reveal that hypogonadism with low serum androgen levels is associated with advanced cancer and induction of most cancer-related symptoms. We designed an ARTFORM study to evaluate the efficacy of androg … en replacement therapy in male advanced cancer patients. The ARTFORM study is an investigator-initiated, randomised controlled trial comparing intramuscle injection of testosterone enanthate with non-ad-ministration in male advanced cancer patients with non-curative locally advanced or metastatic lesions. Serum total and free testosterone levels are measured and patients with low testosterone level are randomised. The primary endpoint is the difference in validated health-related quality of life questionnaires at week 12. Trial registration of the ARTFORM study is assigned to University hospital Medical Information Network, Center identifier UMIN 000010939. © 2017, University of Tokushima. All rights reserved. 続きを見る

URL:

http://hdl.handle.net/2297/00049516

タイトル・著者・出版者が同じ資料

詳細

主題:	Advanced cancer; Androgen replacement therapy; Health-related quality of life; Randomised controlled trial; Testosterone
受理日:	2017

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