※一部利用できない機能があります
Syntheses of several cyclopentano-monoterpene lactones using 1,3-dioxin vinylogous ester
- フォーマット:
- 論文
- 責任表示:
- Ohba, Masashi ; Haneishi, Tsuyoshi ; Fujii, Tozo
- 言語:
- 英語
- 出版情報:
- 日本薬学会, 1995-01-15
- 著者名:
- 掲載情報:
- Chemical & pharmaceutical bulletin
- ISSN:
- 0009-2363
- 巻:
- 43
- 通号:
- 1
- 開始ページ:
- 26
- 終了ページ:
- 31
- バージョン:
- publisher
- 概要:
- Formal syntheses of (±)-boschnialactone (5) and three cyclopentano-monoterpene lactones [i.e., (±)-(iridomyrmecin (6), (±)-isoiridomyrmecin (7), and (±)-allodolicholactone (8)] have been accomplished in the form of the syntheses of 2-(methoxymethyl)-3-methyl-2-cyclopenten-1-one (11) and (±)-(4aα,7α,7aα)-hexahydro-7-methylcyclopenta[c]pyran-3(1H)-one … (19), respectively, starting from 6,7-dihyd;ocyclopenta-1,3-dioxin-5(4H)-one (2). A synthesis of (±)-isodehydroiridomyrmecin (9) has also been achieved through a route including direct substitution of the hydroxy group of 2-(tert-butyldimethylsilyloxymethyl)-3- methyl-2-cyclopenten-1-ol (22) with 1-(tert-butyldimethylsilyloxy)-1-methoxyethene (23) as a key step. 続きを見る
- URL:
- http://hdl.handle.net/2297/7602