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| 1.
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田中, 源吾 ; 野村, 律夫 ; Tanaka, Gengo ; Nomura, Ritsuo
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金沢大学国際基幹教育院GS教育系<br />島根半島に分布する中部中新統古江層より，介形虫化石群を報告した．本群集はMacrocypris sp., Palmoconcha saboyamensis, Falsobuntonia hayam
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iiおよびPalmenella limicolaで特徴づけられる．同様なMacrocypris属が卓越する群集は，現在の島根半島沖の寒冷な下部陸棚域に認められる．このことから，本化石群は下部陸棚の環境を示唆すると考えられる．<br />This report provides the first description of ostracod assemblages from the Middle Miocene Furue Formation, Shimane Peninsula, Southwest Japan. The assemblage consists mainly of Macrocypris sp., Palmoconcha saboyamensis, Falsobuntonia hayamii and Palmenella limicola. Based on a comparison among Recent ostracod assemblages, the reported fossil assemblage indicates a cool lower-shelf environment similar to the Recent off Shimane Peninsula.
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| 2.
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Tanaka, Gengo ; Smith, Robin J. ; Siveter, David J. ; Parker, Andrew R. ; 田中, 源吾
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金沢大学国際基幹教育院GS教育系<br />Compound eyes are common in decapod crustaceans. Decapods have an abundant post-Palaeozoic fossil
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record, but hitherto morphological information about their eyes has been mainly restricted to Recent material. Here we report the discovery of compound eyes recovered from acetic acid residues of two fish-bearing nodules from the Cretaceous Santana Formation of Brazil; they include what are identified as decapod larval compound eyes. The fossil eyes are comparable to phyllosoma larval eyes because of the following characters: the hemispherical visual surface on a stalked eye; the relatively small-size of the visual surface of the eye; rounded facets are arranged in square arrays in the anterior region; the fact that the neighboring ommatidia are bounded by ridges and/ or grooves; and the more convex inner surface of the cornea lens. This report represents the first description of a three-dimensionally preserved fossil decapod eye. We conclude that the eyes probably represent palinuroid phyllosoma larval eyes and were an adaptation to a planktonic lifestyle. © 2009 Zoological Society of Japan.
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田崎, 和江 ; 鈴木, 祐恵 ; 藤沢, 瑛子 ; Tazaki, Kazue ; Suzuki, Sachie ; Fujisawa, Eiko
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金沢大学理工研究域地球社会基盤学系<br />2007年12月7日7時ごろに韓国泰安半島沖10kmで香港籍タンカーの衝突事故が発生した.3つのタンクから重油と原油が12,547kl流出し海岸一帯が汚染された.万里浦海岸(Mallipo Be
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ach)には厚さ30cmの重油が漂着し汚染が最も深刻であった.韓国中からボランティアが集まり,干潮時に毎日6時間の浄化作業を行った.ボランテイアは政府機関のみならず会社,研究所,地域のクラブ,女性組織なども参加した.また,12月30,31日,1月3日には,カナダ,ドイツ,アメリカ,韓国から約50名の科学者や専門家が浄化計画会議をもった.被害はおよそ300億円といわれている.本研究では事故発生から1ヶ月後の2008年1月5-6日に韓国泰安半島の万里浦海岸と蟻項海岸(Euhang Beach)の汚染調査を行った.現地でのボランテイア活動の様子,大気中の芳香族炭化水素の測定,海水の水質測定,重油の化学成分,微生物による油分解実験結果について報告し,1997年1月に日本で起きたナホトカ号重油流出事故の場合と比較検討した.ナホトカ号のC重油流出量の1.7-2.0倍という韓国史上最大の事故にもかかわらず,1ヶ月弱できれいになった砂海岸の浄化作業は驚異的である.早急な浄化作業の要因を考察し,今後の課題と提言を行った.<br />The oil spill accident occurred when a Hong Kong-registered supertanker (Hebei Spirit) was rammed by a South Korean-owned barge that came unmoored from its tugboat in rough seas about 10km off Mallipo Beach at Taean Peninsula, South Korea. The 3 kinds of oil spill accidents started at 7:00 on December 7th 2007, when a tanker collided with a barge, and blackened once-scenic beach along South Korea's western coast, about 150km, southwest of Seoul. A total of 12,547kl of both heavy oil and crude oil gushed into the ocean, more than twice as much as in South Korea's previous worst spill, in 1995. Local residents worked with about 8,800 peoples of volunteers, civil servants, police officers and military personnel, were engaged in the effort to clear away oil on the region's shores. The seafood, oyster farms and tourism industries in the Taean region have been devastated. Oil blanketed the sand of Mallipo Beach and the rocks of Euhang Beach at Taean Peninsula, South Korea, were studied on January 5-6th 2008, just after one month of the accident. Residents wore overalls, used shovels, buckets, adsorption mats, tatters, oil fences, hand-made adsorption roller, heated water at 50-70℃ washing bath, and high-pressured nozzle to clean up the oil muck. The purification of oil on the sand beach was made so quickly within one month in sandy Mallipo Beach, whereas abundant oil drops between rocks with oil slick on the seawater surface on the rocky beach in Euhang Beach still remain. The oilcontaminated hazard map by Marine Environmental Risk Assessment Research Division, Korea Ocean Research and Development Institute, Korea, reported on December 18-19th 2007. In this study, on-site surveys for checking and observing the oiling condition have started on January 5-6th 2008 one month after the spill at Mallipo Beach and Euhang Beach. The values of pH and EC in two places indicated that the bioremediation process of oil took place under neutral conditions. The analytical data of volatile aromatic hydrocarbon concentrations for 0.5l/min at two beaches indicated that the concentration of toluene is quite higher in the atmosphere than that of C typed heavy oil from the Nakhodka tanker in January 1997 in Japan. In particular, toluene concentrations were unbelievably 100-1000 times higher than those in the Nakhodka tanker accident in Japan. They succeed to cleanup beach within one month by volunteer works of manpower, and keep the clean beautiful seashore. Furthermore, we must find new defensive measure systems which are safe, low cost, easy, and sustainable by using local natural materials without manmade chemical substances. It is right time to act locally in Asian countries and think globally about environmental seawater.
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| 4.
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児玉, 一八 ; 田崎, 和江 ; Kodama, Kazuya ; Tazaki, Kazue
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金沢大学理工研究域地球社会基盤学系<br />In the past 55 years no floods have occurred in Asanogawa River which has no dam. Early on the mo
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rning of July 28th, 2008, localized torrential rain in the area around Asanogawa River in Kanazawa City, Japan, brought inundations, flooding homes, causing landslides, and leaving serious damage. In the upper stream, two houses were destroyed completely by flooding and landslides. The muddy flood water flowed into fields and rice paddies, fruit trees were washed down, and the rice was killed. In several areas where the river narrowed, or at bends, flood waters overflowed the dike. Because of delays in closing the floodgate, the river overflowed at opening in the dike called "Kirikaki".
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| 5.
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Hattori, Yuki ; Gabata, Toshifumi ; Matsui, Osamu ; Mochizuki, Kentaro ; Kitagawa, Hirohisa ; Kayahara, Masato ; Ohta, Tetsuo ; Nakanuma, Yasuni ; 蒲田, 敏文 ; 松井, 修 ; 北川, 裕久 ; 萱原, 正都 ; 太田, 哲生 ; 中沼, 安二
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金沢大学医薬保健研究域医学系<br />Aim: To evaluate retrospectively the correlation between enhancement patterns on dynamic computed to
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mography (CT) and angiogenesis and fibrosis in pancreatic adenocarcinoma. Methods: Twenty-three patients with pancreatic adenocarcinoma underwent dynamic CT and tumor resection. In addition to the absolute and relative enhanced value that was calculated by subtracting the attenuation value on pre-contrast from those on contrast-enhanced CT in each phase, we defined one parameter, "tumor-aorta enhancement ratio", which was calculated by dividing enhancement of pancreatic cancer by enhancement of abdominal aorta in each phase. These enhancement patterns were correlated with the level of vascular endothelial growth factor (VEGF), microvessel density (MVD), and extent of fibrosis. Results: The absolute enhanced value in the arterial phase correlated with the level of VEGF and MVD (P = 0.047, P = 0.001). The relative enhanced value in arterial phase and tumor-aorta enhancement ratio (arterial) correlated with MVD (P = 0.003, P = 0.022). Tumor-aorta enhancement ratio (arterial) correlated negatively with the extent of fibrosis (P = 0.004). The tumors with greater MVD and higher expression of VEGF tended to show high enhancement in the arterial dominant phase. On the other hand, the tumors with a larger amount of fibrosis showed a negative correlation with the grade of enhancement during the arterial phase. Conclusion: Enhancement patterns on dynamic CT correlated with angiogenesis and may be modified by the extent of fibrosis. © 2009 The WJG Press and Baishideng. All rights reserved.
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| 6.
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Sasaki, Motoko ; Araki, Ichiro ; Yasui, Toshiaki ; Kinoshita, Masaru ; Itatsu, Keita ; Nojima, Takayuki ; Nakanuma, Yasuni ; 佐々木, 素子 ; 野島, 孝之 ; 中沼, 安二
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金沢大学医薬保健研究域医学系<br />We report a case of primary localized malignant biphasic mesothelioma of the liver in a 66-year-old
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man associated with asbestosis. The tumor was detected as a hepatic nodule, 4 cm in diameter, in the right lobe (S8 segment) on CT scan. Histopathological examination demonstrated an intrahepatic tumor with central necrosis consisting of a papillary epithelioid pattern on the surface of the liver, microcystic (microglandular or adenomatoid) pattern mainly in the subcapsular area and sarcomatoid pattern intermingled with microcystic pattern in the major part of the hepatic nodular tumor. Tumor cells, especially of epithelioid type, showed distinct immunoreactivity for mesothelial markers (WT-1, calretinin, D2-40, CK5/6, mesothelin, thrombomodulin) and no immunoreactivity for epithelial (adenocarcinoma) markers (CEA, CD15, BerEP4, BG8, MOC31). P53 immunoreactivity was detected focally in papillary epithelioid tumor cells and extensively in microcystic and sarcomatoid components, suggesting that the papillary epithelioid mesothelioma arose on the surface of the liver, and tumor cells showing microcystic and sarcomatoid patterns invaded and grew into the liver. To date, this is the first case of primary localized malignant biphasic mesothelioma of the liver, since all three primary hepatic mesotheliomas reported so far were epithelioid type. © 2009 The WJG Press and Baishideng. All rights reserved.
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| 7.
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Yoshikawa, Seiichi ; Zen, Yoh ; Fujii, Takahiko ; Sato, Yasunori ; Ohta, Tetsuo ; Aoyagi, Yutaka ; Nakanuma, Yasuni ; 全, 陽 ; 佐藤, 保則 ; 太田, 哲生 ; 中沼, 安二
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金沢大学医薬保健研究域医学系<br />AIM: To reveal the characteristics of CD133+ cells in the liver. METHODS: This study examined the hi
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stological characteristics of CD133 + cells in non-neoplastic and neoplastic liver tissues by immunostaining, and also analyzed the biological characteristics of CD133 + cells derived from human hepatocellular carcinoma (HCC) or cholangiocarcinoma cell lines. RESULTS: Immunostaining revealed constant expression of CD133 in non-neoplastic and neoplastic biliary epithelium, and these cells had the immunophenotype CD133+/CK19+/HepPar -1-. A smal l number of CD133+/CK19-/HepPar-1+ cells were also identified in HCC and combined hepatocellular and cholangiocarcinoma. In addition, small ductal structures, resembling the canal of Hering, partly surrounded by hepatocytes were positive for CD133. CD133 expression was observed in three HCC (HuH7, PLC5 and HepG2) and two cholangiocarcinoma cell lines (HuCCT1 and CCKS1). Fluorescence-activated cell sorting (FACS) revealed that CD133+ and CD133-cells derived from HuH7 and HuCCT1 cells similarly produced CD133+ and CD133- cells during subculture. To examine the relationship between CD133+ cells and the side population (SP) phenotype, FACS was performed using Hoechst 33342 and a monoclonal antibody against CD133. The ratios of CD133+/CD133-cells were almost identical in the SP and non-SP in HuH7. In addition, four different cellular populations (SP/CD133+, SP/CD133-, non-SP/CD133+, and non-SP/CD133-) could similarly produce CD133+ and CD133- cells during subculture. CONCLUSION: This study revealed that CD133 could be a biliary and progenitor cell marker in vivo. However, CD133 alone is not sufficient to detect tumor-initiating cells in cell lines. © 2009 The WJG Press and Baishideng. All rights reserved.
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| 8.
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福山, 泰治郎 ; 山本, 政儀 ; 井上, 睦夫 ; 恩田, 裕一 ; 水垣, 滋 ; 成沢, 知広 ; Taijiro Fukuyama, ; Yamamoto, Masayoshi ; Inoue, Mutsuo ; Onda, Yuichi ; Mizugaki, Shigeru ; Narisawa, Tomohiro
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金沢大学環日本海域環境研究センター<br />The Japanese Forest Society Congress 120, Session ID : Pc2-09
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早川, 和一 ; Hayakawa, Kazuichi
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金沢大学理工研究域自然システム学系
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安達, 正明 ; 河村, 昌範 ; 岩尾, 雄太 ; Adachi, Masaaki ; Kawamura, Masanori ; Iwao, Yuuta
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金沢大学理工研究域機械工学系<br />垂直走査型干渉顕微鏡を用いる形状計測法は外部振動の影響を極めて受けやすい．我々は，外部振動の影響を受けない形状測定法の開発を目指して，測定対象とする粗面が作る干渉像の垂直走査に伴う変化から，干渉計の光
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路差変化量を高精度に測定する方法を研究して来た．そして，粗面でも光路差変化量が測定可能であることを確認した．今回は，用いる対物レンズの開口の大きさの測定値への影響を実験的に調べたので報告する.<br />出版者照会後に全文公開
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