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論文
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Heki, Utako ; Fujimura, Masaki ; Ogawa, Haruhiko ; Matsuda, Tamotsu ; Kitagawa, Masanobu
概要:
金沢大学医薬保健研究域医学系<br />A 57-year-old man was admitted to our hospital because of dyspnea and abnormal shadow on chest roent
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genogram. He had received two herbal drugs: Saikokeisikankyou-tou (SKT) for one month and Licium Halimifolium Mil (LHM) for two weeks. After admission, all medication was stopped and his symptoms were gradually diminished. Transbronchial lung biopsy specimens showed interstitial pneumonia. Lymphocyte stimulation test, skin test and challenge test were positive to these herbal drugs. We diagnosed him as drug-induced pneumonitis. This is the first report on pneumonitis caused by Saikokeisikankyou-tou diagnosed by lymphocyte stimulation test, skin test and challenge test.
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| 2.
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論文
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Nomura, Akitaka ; Mizukami, Yuji ; Shimizu, Junji ; Oda, Makoto ; Watanabe, Yoh ; Kamimura, Ryoichi ; Takashima, Tsutomu ; Kitagawa, Masanobu
概要:
金沢大学医薬保健研究域保健学系<br />A case with primary plasmacytoma of the lung is described. The patient, a 55-year-old Japanese fema
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le, who simultaneously had a pulmonary plasmacytoma and bladder carcinoma. The bladder tumor was treated with transurethral resection. Pathologically, the bladder tumor was a non-invasive, papillary transitional cell carcinoma, grade II. The lung tumor was located in the right upper lobe and upper lobectomy was performed. The tumor measured 2.8 x 2.7 x 2.0 cm and had a white-yellowish cut surface. Histologic, electron microscopic and immunohistochemical examinations of the lung tumor revealed monoclonal proliferation of plasma cells (IgA, lambda light chain). There was no evidence of multiple myeloma.
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| 3.
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論文
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Nomura, Akitaka ; Mizukami, Yuji ; Murakami, Shinya ; Shimizu, Junzo ; Watanabe, Yoh ; Kamimura, Ryoichi ; Takashima, Tsutomu ; Kitagawa, Masanobu
概要:
金沢大学医薬保健研究域保健学系<br />A 79-year-old male was admitted to the hospital with the complaint of bloody sputum. Chest X-ray re
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vealed an abnormal shadow in the right upper lobe. Macroscopically, the lesion measured about 3.5 x 2.5 x 2.0 cm with a central cavity containing pus. Histologically, the lesion was composed of interlacing fibroblastic proliferation with abundant plasma cell infiltration and central cavitation. The inner surface of the cavity wall was partially covered by bronchial epithelial cells; there was no cartilage found, suggesting that the lesion had developed from chronic inflammatory processes in relation to ectatic bronchioles. Since the pathogenesis of plasma cell granuloma (PCG) has not been well established, it is probable that this case represents one stage in the development of classic PCG.
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