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馬場, 利人
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土田, 敏典
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加藤, 一栄
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Fujii, Tozo ; Yoshifuji, Shigeyuki ; Hatanaka, Yasumaru ; Yoshida, Kiyoshi ; Ohba, Masashi ; Yamada, Koichiro ; Ohkuma, Mihoko ; Shinoda, Hirotaka ; Mizuno, Denichi
概要:
Seventy-four compounds related to lactams and pyridones were synthesized and their anti-tumor activity was examined using Ehrlich carcinoma cells. 4-(2-Piperidyl) butyric acid hydrochloride was found to have some anti-tumor
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effect on the solid type of Ehrlich carcinoma cells, but no other substances were found to be effective. Correlation between the anti-tumor activity and structure of the tested compounds still remains uncertain.
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