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MRM-GRE法を用いた肝臓の鉄含有量および脂肪含有率の同時測定
- フォーマット:
- 論文
- 責任表示:
- 小野, 絵理 ; 宮地, 利明 ; 大野, 直樹 ; 笠井, 治昌 ; 原, 真咲 ; 芝本, 雄太 ; 川野, 誠 ; 朝日, 美幸
- 言語:
- 日本語
- 出版情報:
- 医用画象情報学会, 2009-01-01
- 著者名:
小野, 絵理 宮地, 利明 大野, 直樹 笠井, 治昌 原, 真咲 芝本, 雄太 川野, 誠 朝日, 美幸 - 掲載情報:
- 医用画像情報学会雑誌 = Japan Society of Imaging and Information Sciences in Medicine
- ISSN:
- 0910-1543
- 巻:
- 26
- 通号:
- 3
- 開始ページ:
- 64
- 終了ページ:
- 67
- バージョン:
- publisher
- 概要:
- 金沢大学医薬保健研究域保健学系<br />We evaluated the R2* (iron content) and fat fraction of the liver tissue simultaneously using modulus and real multiple gradient-echo (MRM-GRE) sequence. On a 1.5-T MRI, modulus images of 7-9 gradient-echoes were … obtained by MRM-GRE sequence at a time. A real part of the first echo image was also reconstructed to differentiate below and above the 50 percent fat fraction. The fat fraction and R2* were obtained from the parameters of a theoretically fitted formula with each echo signal. R2* and fat fraction were measured with MRM-GRE in the phantom and the liver in normal volunteers (n=6) and patients with fatty liver (n=4) . MRI-derived fat fraction of the phantom was in good agreement with the actual value, and R2* of the phantom showed a strongly positive correlation with the actual iron content. MRI-derived fat fraction in fatty liver was significantly higher than that in the normal volunteers. However, no significant difference in R2* was found between fatty liver and normal volunteers. These results show that the MRM-GRE enables to differentiate the causes of signal reduction whether increasing R2*or increasing fat fraction. The MRM-GRE method makes it possible to simply and accurately assess the fat content and the iron content. 続きを見る
- URL:
- http://hdl.handle.net/2297/24703
類似資料:
医用画象情報学会 |
金澤醫科大學十全會 |
医用画象情報学会 |
金沢大学教育学部 |
医用画像情報学会 = MII: Japan Society of Medical Imaging and Information Sciences |
北陸作物・育種学会 / 日本作物学会 |
医用画象情報学会 | |
日本作物学会 = The Crop Science Society of Japan |
金沢大学医学部法医学教室, 法医・鑑識並びに社会医学雑誌発行所 / 金沢大学 Kanazawa University |
日本放射線技術学会 = Japanese Society of Radiological Technology |
金沢大学医学部法医学教室, 法医・鑑識並びに社会医学雑誌発行所 / 金沢大学 Kanazawa University |