A Case of Hypereosinophilia-Associated Multiple Mass Lesions of Liver Showing Non-Granulomatous Eosinophilic Hepatic Necrosis

フォーマット:

論文

責任表示:

Ikeda, Hiroko ; Katayanagi, Kazuyoshi ; Kurumaya, Hiroshi ; Harada, Kenichi ; Sato, Yasunori ; Sasaki, Motoko ; Nakanuma, Yasuni

言語:

英語

出版情報:

Elmer Press, 2011-08-01

著者名:

Ikeda, Hiroko

Katayanagi, Kazuyoshi

Kurumaya, Hiroshi

Harada, Kenichi

Sato, Yasunori

Sasaki, Motoko

Nakanuma, Yasuni

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掲載情報:

Gastroenterology Research, bimonthly

ISSN:

1918-2805      

巻:

4

通号:

4

開始ページ:

168

終了ページ:

173

バージョン:

publisher

概要:

Hypereosinophilic syndrome (HES) is defi ned by elevation more than 1.5×109/L of presence of a peripheral blood count, evidence of organ involvement, and exclusion of secondary eosinophilia such as allergic, vasculitis, drugs, or parasite infection and also clonal eosinophilia. We present the HES case with hepatic involvement. The patient is 70-year-old male. He complained fever and back pain. Blood examination showed marked peripheral … eosinophilia, elevation of transaminase and biliary enzymes. Multiple irregular mass lesions of the liver were pointed out by CT and MRI. The liver biopsy was done for differentiation from malignancy. In parenchyma, hepatic necrotic lesion was observed accompanying severe eosinophilic infi ltration with Charcot-Leyden’s crystals. There was granulomatous reaction. He was diagnosed as HES and got recovery due to steroid therapy. From the review of HES article, the hepatic histology is categorized into four types as below: 1) cholangitis type; 2) chronic active hepatitis type; 3) vasculopathic type, 4) hepatic necrosis type. Our case is classifi ed in hepatic necrosis type. This type seems to be important to distinguish malignant tumor and also visceral larva migrans by liver biopsy. 続きを見る

URL:

http://hdl.handle.net/2297/34940