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1.
論文 |
Kitamura, Keiichiro ; Takata, Shigeo ; Futamata, Shigeo ; Hashimoto, Takuma ; Sakagami, Satoru ; Kobasashi, Ken-ichi
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論文 |
Kitamura, Keiichiro ; Takata, Shigeo ; Hashimoto, Takuma ; Futamata, Hideo ; Sakagami, Satoru ; Shimakura, Atsuhiro ; Kobayashi, Ken-ichi
概要:
Aim of this study was to assess the relation of generalized obesity and fat distribution to sympathetic and parasympathetic components ofheart rate in healthy young subjects. We recorded ECG continuously in the supine and standing
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position with pacing respiration at 0.25Hz for 5 min in 47 healthy young female. Habitus was represented by body mass index, as an index of generalized adiposity, and by the ratio of waist-to-hip girth (waist/hip ratio), as an index of centripetal fat distribution. A spectral analysis of R-R variability from 256-sec series interbeat interval in each position provided markers of sympathetic nerve activity (ratio of low frequency component to high frequency component (LF /HF ratio) in the standing position), and vagal activity (HF power in the supine position). LF /HF ratio in the standing position was positively correlated with both waist/ hip ratio (r=0.366, p<0.02) and waist girth (r= 0.317, p<0.04), but not correlated with body mass index (p=0.904). HF power in the supine position was not correlated with waist/hip ratio (p=0.893), waist girth (p= 0.907) or body .mass index (p=0.454). These results suggest that, in healthy young female, centripetal fat distribution is one of the determinants of the cardiac sympathetic activity, but not the cardiac vagal activity.
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