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Chemokines
- フォーマット:
- 論文
- 責任表示:
- Mukaida, Naofumi
- 言語:
- 英語
- 出版情報:
- Elsevier, 2014-12-15
- 著者名:
- Mukaida, Naofumi
- 掲載情報:
- Reference Module in Biomedical Research
- 巻:
- 2014
- 開始ページ:
- 1056
- バージョン:
- author
- 概要:
- Chemokines are a family of structurally related cytokines with four cysteines at their well-conserved positions. Most chemokines are secreted proteins with a molecular weight about 10. kDa and their α helix structure at carboxyl-terminal portion is responsible for preferential binding to proteoglycans on the vascular endothelial cells and to extracellular matrix proteins. Chemokine receptors comprise a large branch of the rhodopsin family of … cell-surface G-protein-coupled receptors with seven-transmembrane domains. Chemokines bind their corresponding receptors, thereby modulating the movement and functions of their target cells, particularly leukocyte trafficking, under physiological and pathological conditions. © 2014 Elsevier Inc. All rights reserved.<br />[Book Chapter] 続きを見る
- URL:
- http://hdl.handle.net/2297/43880
類似資料:
Elsevier | |
WJG Press / Baishideng Publishing Group Co., Limited |
Nature Publishing Group |
W J G Press / Baishideng Publishing Group Co | |
日本臨床免疫学会 = The Japan Society for Clinical Immunology |
Hindawi Publishing Corporation |
日本臨床免疫学会 = The Japan Society for Clinical Immunology |