1.

論文

論文
Maruta, Takahiro ; Yoshikawa, Hiroaki ; Fukasawa, Shuichi ; Umeshita, Sho ; Inaoka, Yoshihiro ; Edahiro, Shigeki ; Kado, Hirotsugu ; Motozaki, Yuko ; Iwasa, Kazuo ; Yamada, Masahito
出版情報: Journal of Neuroimmunology.  208  pp.125-129,  2009-03-31.  Elsevier
URL: http://hdl.handle.net/2297/16736
概要: 金沢大学保健管理センター<br />To investigate autoantibodies related to excitation-contraction (E-C) coupling in patients with myasth enia gravis (MG), we developed a novel method to detect autoantibodies against dihydropyridine receptor (DHPR). Using this method, we detected DHPR antibody in 37% (11 out of 30) of MG patients with thymoma. Antibodies were not detected in normal nor disease controls. The titer of DHPR antibodies showed no significant correlation with autoantibodies to acetylcholine nor ryanodine receptors. The DHPR antibody is another marker for thymoma in MG, and it might have some role in clinical symptoms related to E-C coupling. © 2009 Elsevier B.V. All rights reserved. 続きを見る
2.

論文

論文
Maruta, Takahiro ; Yoshikawa, Hiroaki ; Fukasawa, Shuichi ; Umeshita, Sho ; Inaoka, Yoshihiro ; Edahiro, Shigeki ; Kado, Hirotsugu ; Motozaki, Yuko ; Iwasa, Kazuo ; Yamada, Masahito
出版情報: Journal of Neuroimmunology.  208  pp.125-129,  2009-03-31.  Elsevier BV
URL: http://hdl.handle.net/2297/17330
概要: 金沢大学保健管理センター<br />To investigate autoantibodies related to excitation-contraction (E-C) coupling in patients with myasth enia gravis (MG), we developed a novel method to detect autoantibodies against dihydropyridine receptor (DHPR). Using this method, we detected DHPR antibody in 37% (11 out of 30) of MG patients with thymoma. Antibodies were not detected in normal nor disease controls. The titer of DHPR antibodies showed no significant correlation with autoantibodies to acetylcholine nor ryanodine receptors. The DHPR antibody is another marker for thymoma in MG, and it might have some role in clinical symptoms related to E-C coupling. © 2009 Elsevier B.V. All rights reserved. 続きを見る